The relationship between prostatic intraepithelial neoplasia and prostate cancer: critical issues

MJ Haggman, JA Macoska, KJ Wojno… - The Journal of …, 1997 - Elsevier
PURPOSE: Prostatic intraepithelial neoplasia (PIN) is often considered to be a premalignant
lesion and the main precursor of invasive carcinoma of the prostate. We evaluated the …

Prostatic intraepithelial neoplasia

DG Bostwick - Current urology reports, 2000 - Springer
High-grade prostatic intraepithelial neoplasia (PIN) is now accepted as the most likely pre-
invasive stage of adenocarcinoma, a decade after its first formal description. PIN has a high …

High grade prostatic intraepithelial neoplasia. The most likely precursor of prostate cancer

DG Bostwick - Cancer, 1995 - Wiley Online Library
The search for the precursor of prostatic adenocarcinoma has focused in recent years on the
spectrum of histopathologic changes referred to as high grade prostatic intraepithelial …

Morphological identification of the patterns of prostatic intraepithelial neoplasia and their importance

R Montironi, R Mazzucchelli, F Algaba… - Journal of clinical …, 2000 - jcp.bmj.com
High grade prostatic intraepithelial neoplasia (PIN) is the most likely precursor of prostatic
carcinoma. PIN has a high predictive value as a marker for carcinoma, and its identification …

[HTML][HTML] Prostatic intraepithelial neoplasia: an overview

MK Brawer - Reviews in urology, 2005 - ncbi.nlm.nih.gov
Prostatic intraepithelial neoplasia (PIN) is the most established precursor of prostatic
carcinoma. The presence of prominent nucleoli within an existing duct structure is an easy …

[HTML][HTML] High-grade prostatic intraepithelial neoplasia

DG Bostwick, J Qian - Modern pathology, 2004 - Elsevier
High-grade prostatic intraepithelial neoplasia (PIN) is now accepted as the most likely
preinvasive stage of adenocarcinoma, almost two decades after its first formal description …

Prostatic intraepithelial neoplasia is a risk factor for cancer.

DG Bostwick - Seminars in urologic oncology, 1999 - europepmc.org
High-grade prostatic intraepithelial neoplasia (PIN) is now accepted as the most likely
preinvasive stage of adenocarcinoma, a decade after its first formal description. PIN has a …

Diagnosis of prostatic intraepithelial neoplasia: Prostate working group 1 consensus report

D Bostwick, R Montironi… - Scandinavian Journal of …, 2000 - Taylor & Francis
High-grade prostatic intraepithelial neoplasia (PIN) is the most likely precursor of prostatic
carcinoma. PIN has a high predictive value as a marker for carcinoma, and its identification …

Molecular biology of prostatic intraepithelial neoplasia

DG Bostwick, A Pacelli, A Lopez‐Beltran - The Prostate, 1996 - Wiley Online Library
High‐grade PIN is the most likely precursor of prostatic adenocarcinoma, according to
virtually all available evidence to date. The clinical importance of recognizing PIN is based …

Prostatic intraepithelial neoplasia: its morphological and molecular diagnosis and clinical significance

R Montironi, R Mazzucchelli, A Lopez‐Beltran… - BJU …, 2011 - Wiley Online Library
What's known on the subject? and What does the study add? High grade prostatic
intraepithelial neoplasia (HGPIN) is the precursor lesion to some forms of adenocarcinoma …