Tissue selenium levels in selenium-supplemented rats and their relevance in mammary cancer protection

C Ip, C Hayes - Carcinogenesis, 1989 - academic.oup.com
The present study was designed to investigate whether there is any correlation between the
anticarcinogenic efficacy of selenium (Se) compounds and tissue Se retention under high …

Novel strategies in selenium cancer chemoprevention research

C Ip, HE Ganther - Selenium in biology and human health, 1994 - Springer
Experimental studies with rodents indicate that selenium supplementation at levels above
the dietary requirement is capable of protecting against tumorigenesis induced by chemical …

Effect of an inorganic and organic form of dietary selenium on the promotional stage of mammary carcinogenesis in the rat

HJ Thompson, LD Meeker, S Kokoska - Cancer research, 1984 - AACR
The relative effectiveness of either sodium selenite or selenomethionine in the inhibition of
mammary carcinogenesis was studied in virgin female Sprague-Dawley rats. In one …

Chemical form of selenium, critical metabolites, and cancer prevention

C Ip, C Hayes, RM Budnick, HE Ganther - Cancer research, 1991 - AACR
Methylated selenides are prominent metabolites at the dietary levels used for obtaining
anticarcinogenic effects with selenium. The present study reports the chemopreventive …

Chemoprevention with triphenylselenonium chloride in selenium-deficient rats.

C Ip, DJ Lisk, HE Ganther - Anticancer research, 2000 - europepmc.org
Cancer chemoprevention by high levels of selenium, including compounds like sodium
selenite or selenomethionine, is generally not accompanied by increases in known …

Activity of methylated forms of selenium in cancer prevention

C Ip, HE Ganther - Cancer research, 1990 - AACR
The anticarcinogenic activity of selenium in animal models is well established. The active
forms of selenium involved have not been identified to date, but conversion of selenium via …

Stage specificity of selenium-mediated inhibition of mouse mammary tumorigenesis

D Medina, HW Lane - Biological Trace Element Research, 1983 - Springer
The experiments reported herein examined the inhibitory role of selenium in chemical
carcinogen-induced mouse mammary tumorigenesis. The results from four different …

Factors influencing the anticarcinogenic efficacy of selenium in dimethylbenz [a] anthracene-induced mammary tumorigenesis in rats

C Ip - Cancer Research, 1981 - AACR
The present study was designed to investigate the effect of selenium supplementation on
dimethylbenz [a] anthracene-induced mammary tumorigenesis in female Sprague-Dawley …

Temporal changes in tissue glutathione in response to chemical form, dose, and duration of selenium treatment: Relevance to cancer chemoprevention by selenium

HJ Thompson, C Ip - Biological trace element research, 1991 - Springer
Selenium has been reported to affect glutathione (GSH) concentrations in short-term animal-
feeding experiments. Given the central role that this tripeptide plays in maintaining cellular …

Inhibitory effect of selenomethionine on the growth of three selected human tumor cell lines

C Redman, JA Scott, AT Baines, JL Basye, LC Clark… - Cancer Letters, 1998 - Elsevier
Selenium supplementation has been shown for many years to work as an anticarcinogenic
agent both in epidemiology and in in vitro studies. Selenium supplementation has recently …