Cancer immunotherapy has achieved multiple clinical benefits and has become an
indispensable component of cancer treatment. Targeting tumor-specific antigens, also …

Neoantigens are tumor-specific proteins and peptides that can be highly immunogenic.
Immune-mediated tumor rejection is strongly associated with cytotoxic responses to …

The recent success of cancer immunotherapies has highlighted the benefit of harnessing the
immune system for cancer treatment. Vaccines have a long history of promoting immunity to …

Within the past decade, the field of immunotherapy has revolutionized the treatment of many
cancers with the development and regulatory approval of various immune-checkpoint …

Cancer immunotherapies are treatments that use drugs or cells to activate patients' own
immune systems against cancer cells. Among them, cancer vaccines have recently been …

Immunotherapy represents a promising strategy for cancer treatment that utilizes immune
cells or drugs to activate the patient's own immune system and eliminate cancer cells. One of …

Immunotherapy treatments harnessing the immune system herald a new era of personalized
medicine, offering considerable benefits for cancer patients. Over the past years, tumor …

Cancer vaccines have encountered their ideal personalized partner along with evidence for
great breakthroughs in the identification and synthesis of neoantigens. Individual cancer …

The process of tumorigenesis leaves a series of indelible genetic changes in tumor cells,
that when expressed, have the potential to be tumor-specific immune targets. Neoantigen …

Personal neoantigen–based cancer vaccines are designed to target antigens arising from
tumor-specific mutations within individual cancers and present a tremendous opportunity to …