[HTML][HTML] Exposure to human relevant mixtures of halogenated persistent organic pollutants (POPs) alters neurodevelopmental processes in human neural stem cells …
Halogenated persistent organic pollutants (POPs) like perfluorinated alkylated substances
(PFASs), brominated flame retardants (BFRs), organochlorine pesticides and …
(PFASs), brominated flame retardants (BFRs), organochlorine pesticides and …
[HTML][HTML] Combining in vitro assays and mathematical modelling to study developmental neurotoxicity induced by chemical mixtures
F Pistollato, D Carpi, E Mendoza-de Gyves… - Reproductive …, 2021 - Elsevier
Prenatal and postnatal co-exposure to multiple chemicals at the same time may have
deleterious effects on the developing nervous system. We previously showed that chemicals …
deleterious effects on the developing nervous system. We previously showed that chemicals …
Assessment of developmental neurotoxicity induced by chemical mixtures using an adverse outcome pathway concept
F Pistollato, EM de Gyves, D Carpi, SK Bopp… - Environmental …, 2020 - Springer
Background In light of the vulnerability of the developing brain, mixture risk assessment
(MRA) for the evaluation of developmental neurotoxicity (DNT) should be implemented …
(MRA) for the evaluation of developmental neurotoxicity (DNT) should be implemented …
Assessing developmental neurotoxicity of emerging environmental chemicals using multiple in vitro models: A comparative analysis
S Li, M Zhao, S Zhang, R Yang, N Yin, H Wang… - Environmental …, 2024 - Elsevier
Newly synthesized chemicals are being introduced into the environment without undergoing
proper toxicological evaluation, particularly in terms of their effects on the vulnerable …
proper toxicological evaluation, particularly in terms of their effects on the vulnerable …
Antenatal exposure to plastic pollutants: study of the bisphenols and perfluoroalkyls effects on human stem cell models
G Gaggi, A Di Credico, F Barbagallo, P Ballerini… - Exposure and …, 2024 - Springer
Endocrine disruptors (EDs), such as Bisphenols (BPs) and Perfluoroalkyls (PFs), are a class
of plastic pollutants widely used in industrial applications. Human exposure to these …
of plastic pollutants widely used in industrial applications. Human exposure to these …
[HTML][HTML] Differential susceptibility of rat primary neurons and neural stem cells to PFOS and PFOA toxicity
P Pierozan, O Karlsson - Toxicology Letters, 2021 - Elsevier
Per and polifluorinated substances (PFAS) are ubiquitous and persistent contaminants.
Studies have indicated that fetuses and infants can be exposed to these chemicals in utero …
Studies have indicated that fetuses and infants can be exposed to these chemicals in utero …
Non–dioxin-like polychlorinated biphenyls interfere with neuronal differentiation of embryonic neural stem cells
R Tofighi, WN Wan Ibrahim, P Rebellato… - Toxicological …, 2011 - academic.oup.com
Developmental exposure to food contaminants, such as polychlorinated biphenyls (PCBs),
has been considered as a possible cause of neurodevelopmental disorders. We have …
has been considered as a possible cause of neurodevelopmental disorders. We have …
[HTML][HTML] Strategies to improve the regulatory assessment of developmental neurotoxicity (DNT) using in vitro methods
A Bal-Price, F Pistollato, M Sachana, SK Bopp… - Toxicology and applied …, 2018 - Elsevier
Currently, the identification of chemicals that have the potential to induce developmental
neurotoxicity (DNT) is based on animal testing. Since at the regulatory level, systematic …
neurotoxicity (DNT) is based on animal testing. Since at the regulatory level, systematic …
A mixture of persistent organic pollutants and perfluorooctanesulfonic acid induces similar behavioural responses, but different gene expression profiles in zebrafish …
A Khezri, TWK Fraser, R Nourizadeh-Lillabadi… - International journal of …, 2017 - mdpi.com
Persistent organic pollutants (POPs) are widespread in the environment and some may be
neurotoxic. As we are exposed to complex mixtures of POPs, we aimed to investigate how a …
neurotoxic. As we are exposed to complex mixtures of POPs, we aimed to investigate how a …
Developmental neurotoxicity of persistent organic pollutants: an update on childhood outcome
SA Berghuis, AF Bos, PJJ Sauer, E Roze - Archives of toxicology, 2015 - Springer
Organohalogens are persistent organic pollutants that have a wide range of chemical
application. There is growing evidence that several of these chemical compounds interfere …
application. There is growing evidence that several of these chemical compounds interfere …