Chronic obstructive pulmonary disease exacerbations in the COPDGene study: associated radiologic phenotypes

MLK Han, EA Kazerooni, DA Lynch, LX Liu, S Murray… - Radiology, 2011 - pubs.rsna.org
Purpose To test the hypothesis—given the increasing emphasis on quantitative computed
tomographic (CT) phenotypes of chronic obstructive pulmonary disease (COPD)—that a …

Imaging advances in chronic obstructive pulmonary disease. Insights from the genetic epidemiology of chronic obstructive pulmonary disease (COPDGene) study

SP Bhatt, GR Washko, EA Hoffman… - American journal of …, 2019 - atsjournals.org
The Genetic Epidemiology of Chronic Obstructive Pulmonary Disease (COPDGene) study,
which began in 2007, is an ongoing multicenter observational cohort study of more than …

Clinical and computed tomographic predictors of chronic bronchitis in COPD: a cross sectional analysis of the COPDGene study

V Kim, A Davey, AP Comellas, MK Han, G Washko… - Respiratory …, 2014 - Springer
Background Chronic bronchitis (CB) has been related to poor outcomes in Chronic
Obstructive Pulmonary Disease (COPD). From a clinical standpoint, we have shown that …

[HTML][HTML] Identification of a predominant COPD phenotype in clinical practice

M Pistolesi, G Camiciottoli, M Paoletti, C Marmai… - Respiratory …, 2008 - Elsevier
BACKGROUND: Chronic obstructive pulmonary disease (COPD) is characterized by airflow
limitation caused by small airways increased resistance and/or terminal airspaces …

Genetic association analysis of functional impairment in chronic obstructive pulmonary disease

CP Hersh, DL DeMeo, R Lazarus… - American journal of …, 2006 - atsjournals.org
Rationale: Patients with severe chronic obstructive pulmonary disease (COPD) may have
varying levels of disability despite similar levels of lung function. This variation may reflect …

Clinical significance of radiologic characterizations in COPD

MLK Han, B Bartholmai, LX Liu, S Murray… - COPD: Journal of …, 2009 - Taylor & Francis
ABSTRACT COPD is a heterogeneous disorder with clinical assessment becoming
increasingly multidimensional. We hypothesized HRCT phenotype would strongly influence …

[HTML][HTML] The role of CT scanning in multidimensional phenotyping of COPD

M Bafadhel, I Umar, S Gupta, JV Raj, DD Vara… - Chest, 2011 - Elsevier
Background COPD is a heterogeneous disease characterized by airflow obstruction and
diagnosed by lung function. CT imaging is emerging as an important, noninvasive tool in …

Relationship between quantitative CT metrics and health status and BODE in chronic obstructive pulmonary disease

CH Martinez, YH Chen, PM Westgate, LX Liu, S Murray… - Thorax, 2012 - thorax.bmj.com
Background The value of quantitative CT (QCT) to identify chronic obstructive pulmonary
disease (COPD) phenotypes is increasingly appreciated. The authors hypothesised that …

Airway wall thickening and emphysema show independent familial aggregation in chronic obstructive pulmonary disease

BD Patel, HO Coxson, SG Pillai… - American journal of …, 2008 - atsjournals.org
Rationale: It is unclear whether airway wall thickening and emphysema make independent
contributions to airflow limitation in chronic obstructive pulmonary disease (COPD) and …

Molecular biomarkers for quantitative and discrete COPD phenotypes

S Bhattacharya, S Srisuma, DL DeMeo… - American journal of …, 2009 - atsjournals.org
Chronic obstructive pulmonary disease (COPD) is an inflammatory lung disorder with
complex pathological features and largely unknown etiology. The identification of …