Exacerbations of chronic obstructive pulmonary disease (COPD) are defined as sustained
worsening of a patient's condition beyond normal day-to-day variations that is acute in onset …

Rationale In COPD patients, mortality risk is influenced by age, severity of respiratory
disease, and comorbidities. With an unbiased statistical approach we sought to identify …

Computed tomographic based indices of emphysematous lung destruction may highlight
differences in disease pathogenesis and further enable the classification of subjects with …

COPD is a heterogeneous syndrome. Many COPD subtypes have been proposed, but there
is not yet consensus on how many COPD subtypes there are and how they should be …

Background The COPD “frequent exacerbator” phenotype is usually defined by at least two
treated exacerbations per year and is associated with a huge impact on patient health …

Chronic obstructive pulmonary disease (COPD) is a significant cause of global morbidity
and mortality. Previous studies have shown that COPD aggregates in families, suggesting a …

Summary⇓ Chronic obstructive pulmonary disease (COPD) is a leading cause of morbidity
and mortality in the USA, and it remains one of the few diseases that continues to increase …

Significant heterogeneity of clinical presentation and disease progression exists within
chronic obstructive pulmonary disease (COPD). Although FEV1 inadequately describes this …

The pathology and impact of chronic obstructive pulmonary disease (COPD) results from an
abnormal inflammatory process resulting in tissue damage with ineffective repair in …

BACKGROUND: COPD patients have varying degrees of airways disease and emphysema.
CT scanning can differentiate these pathological subtypes. We evaluated airway dimensions …