The role of eosinophils in bullous pemphigoid: a developing model of eosinophil pathogenicity in mucocutaneous disease
Bullous pemphigoid (BP) is an autoimmune blistering disease which carries a significant
mortality and morbidity. While historically BP has been characterized as an IgG driven …
mortality and morbidity. While historically BP has been characterized as an IgG driven …
The intersection of IgE autoantibodies and eosinophilia in the pathogenesis of bullous pemphigoid
KN Messingham, TP Crowe, JA Fairley - Frontiers in immunology, 2019 - frontiersin.org
Bullous pemphigoid (BP) is an autoimmune blistering disease characterized by
autoantibodies targeting cellular adhesion molecules. While IgE autoantibodies are …
autoantibodies targeting cellular adhesion molecules. While IgE autoantibodies are …
[HTML][HTML] Eosinophils mediate tissue injury in the autoimmune skin disease bullous pemphigoid
Eosinophils are typically associated with unique inflammatory settings, including allergic
inflammation and helminth infections. However, new information suggests that eosinophils …
inflammation and helminth infections. However, new information suggests that eosinophils …
Evidence for a role of eosinophils in blister formation in bullous pemphigoid
Background Bullous pemphigoid (BP) is an autoimmune bullous disease of the skin
characterized by subepidermal blister formation due to tissue‐bound and circulating …
characterized by subepidermal blister formation due to tissue‐bound and circulating …
Human eosinophils express the high affinity IgE receptor, FcεRI, in bullous pemphigoid
KN Messingham, HM Holahan, AS Frydman… - PloS one, 2014 - journals.plos.org
Bullous pemphigoid (BP) is an autoimmune blistering disease mediated by autoantibodies
targeting BP180 (type XVII collagen). Patient sera and tissues typically have IgG and IgE …
targeting BP180 (type XVII collagen). Patient sera and tissues typically have IgG and IgE …
Eosinophil Cationic Protein (ECP), a predictive marker of bullous pemphigoid severity and outcome
D Giusti, G Gatouillat, S Le Jan, J Plée, P Bernard… - Scientific Reports, 2017 - nature.com
Bullous Pemphigoid (BP) is an inflammatory rare autoimmune bullous dermatosis, which
outcome cannot be predicted through clinical investigations. Eosinophils are the main …
outcome cannot be predicted through clinical investigations. Eosinophils are the main …
Peripheral eosinophilia in bullous pemphigoid: prevalence and influence on the clinical manifestation
K Kridin - British Journal of Dermatology, 2018 - academic.oup.com
Background Peripheral eosinophilia has been reported in 50–60% of patients with bullous
pemphigoid (BP) and correlated positively with disease severity. Objectives To establish an …
pemphigoid (BP) and correlated positively with disease severity. Objectives To establish an …
Elevated levels of eotaxin and interleukin‐5 in blister fluid of bullous pemphigoid: correlation with tissue eosinophilia
M Wakugawa, K Nakamura, H Hino… - British Journal of …, 2000 - academic.oup.com
Background Bullous pemphigoid (BP) often provokes blood and tissue eosinophilia, which
suggests that some chemoattractants modulate the eosinophil infiltration in BP. Eotaxin, a …
suggests that some chemoattractants modulate the eosinophil infiltration in BP. Eotaxin, a …
IgE autoreactivity in bullous pemphigoid: eosinophils and mast cells as major targets of pathogenic immune reactants
PC Freire, CH Muñoz, G Stingl - British Journal of Dermatology, 2017 - academic.oup.com
Background Bullous pemphigoid (BP) is an autoimmune disease characterized by tense
blisters that are usually preceded by urticarial eruptions. Affected patients exhibit IgG and/or …
blisters that are usually preceded by urticarial eruptions. Affected patients exhibit IgG and/or …
Unraveling the significance of IgE autoantibodies in organ-specific autoimmunity: lessons learned from bullous pemphigoid
KAN Messingham, HM Holahan, JA Fairley - Immunologic research, 2014 - Springer
Bullous pemphigoid (BP), a cutaneous autoimmune blistering disease, has provided a
useful model to elucidate a role for IgE in autoimmunity. IgE antibodies specific for the …
useful model to elucidate a role for IgE in autoimmunity. IgE antibodies specific for the …
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