Why is the biodegradation of polyfluorinated compounds so rare?

LP Wackett - Msphere, 2021 - Am Soc Microbiol
Thousands of heavily fluorinated chemicals are found in the environment, impact human
and ecosystem health, and are relatively resistant to biological and chemical degradation …

Nothing lasts forever: understanding microbial biodegradation of polyfluorinated compounds and perfluorinated alkyl substances

LP Wackett - Microbial biotechnology, 2022 - Wiley Online Library
Poly‐and perfluorinated chemicals, including perfluorinated alkyl substances (PFAS), are
pervasive in today's society, with a negative impact on human and ecosystem health …

Strategies for the biodegradation of polyfluorinated compounds

LP Wackett - Microorganisms, 2022 - mdpi.com
Many cite the strength of C–F bonds for the poor microbial biodegradability of
polyfluorinated organic compounds (PFCs). However, commercial PFCs almost invariably …

A review of microbial degradation of per-and polyfluoroalkyl substances (PFAS): Biotransformation routes and enzymes

A Berhanu, I Mutanda, J Taolin, MA Qaria… - Science of the Total …, 2023 - Elsevier
Since the 1950s, copious amounts of per-and polyfluoroalkyl substances (PFAS)(dubbed
“forever chemicals”) have been dumped into the environment, causing heavy contamination …

Microwell Fluoride Screen for Chemical, Enzymatic, and Cellular Reactions Reveals Latent Microbial Defluorination Capacity for −CF3 Groups

MD Bygd, KG Aukema, JE Richman… - Applied and …, 2022 - Am Soc Microbiol
The capacity to defluorinate polyfluorinated organic compounds is a rare phenotype in
microbes but is increasingly considered important for maintaining the environment. New …

A review: Per-and polyfluoroalkyl substances—Biological degradation

D Grgas, A Petrina, T Štefanac, D Bešlo… - Toxics, 2023 - mdpi.com
Per-and polyfluoroalkyl substances (PFASs), highly stable synthetic organic compounds
with multiple carbon-fluorine bonds, are emerging as environmental contaminants, toxic …

Microbial degradation of polyfluoroalkyl chemicals in the environment: a review

J Liu, SM Avendaño - Environment international, 2013 - Elsevier
Polyfluoroalkyl chemicals containing perfluoroalkyl moieties have been widely used in
numerous industrial and commercial applications. Many polyfluoroalkyl chemicals are …

[引用][C] Pseudomonas: versatile biocatalysts for PFAS

LP Wackett - Environmental microbiology, 2022 - Wiley Online Library
Many believe in the concept expressed by the old saying,'A byrd in hand–is worth ten flye at
large,'(Rhodes, 1571), although the number at large may vary. Similarly, using model …

Evolutionary obstacles and not C–F bond strength make PFAS persistent

LP Wackett - Microbial Biotechnology, 2024 - Wiley Online Library
The fate of organic matter in the environment, including anthropogenic chemicals, is largely
predicated on the enzymatic capabilities of microorganisms. Microbes readily degrade, and …

Biodegradation and biotransformation of organofluorine compounds

CD Murphy - Biotechnology letters, 2010 - Springer
The carbon–fluorine bond is one of the strongest in nature, and the increasing use of
organofluorine compounds in agriculture, human and veterinary medicine, and industry has …