CD56bright cells differ in their KIR repertoire and cytotoxic features from CD56dim NK cells
R Jacobs, G Hintzen, A Kemper, K Beul… - European journal of …, 2001 - Wiley Online Library
In this study we present new differential characteristics of NK cells expressing CD56 surface
antigen in low (CD56dim) or high (CD56bright) density. In contrast to CD56bright NK cells …
antigen in low (CD56dim) or high (CD56bright) density. In contrast to CD56bright NK cells …
CD94 surface density identifies a functional intermediary between the CD56bright and CD56dim human NK-cell subsets
J Yu, HC Mao, M Wei, T Hughes… - Blood, The Journal …, 2010 - ashpublications.org
Human CD56bright natural killer (NK) cells possess little or no killer immunoglobulin-like
receptors (KIRs), high interferon-γ (IFN-γ) production, but little cytotoxicity. CD56dim NK cells …
receptors (KIRs), high interferon-γ (IFN-γ) production, but little cytotoxicity. CD56dim NK cells …
Human lymphoid tissues harbor a distinct CD69+ CXCR6+ NK cell population
G Lugthart, JE Melsen, C Vervat… - The Journal of …, 2016 - journals.aai.org
Abstract Knowledge of human NK cells is based primarily on conventional CD56 bright and
CD56 dim NK cells from blood. However, most cellular immune interactions occur in …
CD56 dim NK cells from blood. However, most cellular immune interactions occur in …
CD56bright natural killer (NK) cells: an important NK cell subset
Human natural killer (NK) cells can be subdivided into different populations based on the
relative expression of the surface markers CD16 and CD56. The two major subsets are …
relative expression of the surface markers CD16 and CD56. The two major subsets are …
Induction of CD16+ CD56bright NK Cells with Antitumour Cytotoxicity not only from CD16− CD56bright NK Cells but also from CD16− CD56dim NK Cells
E Takahashi, N Kuranaga, K Satoh… - Scandinavian …, 2007 - Wiley Online Library
The aim of this study was to examine the effect of cytokines on different subsets of NK cells,
while especially focusing on CD16− CD56dim cells and CD16− CD56bright cells. When …
while especially focusing on CD16− CD56dim cells and CD16− CD56bright cells. When …
The small subset of CD56brightCD16– natural killer cells is selectively responsible for both cell proliferation and interferon‐γ production upon interaction with …
The encounter of NK cells with dendritic cells (DC) undergoing maturation may result in the
induction of NK cell proliferation. Whether such proliferation involves most NK cells or just a …
induction of NK cell proliferation. Whether such proliferation involves most NK cells or just a …
The biology of human natural killer-cell subsets
MA Cooper, TA Fehniger, MA Caligiuri - Trends in immunology, 2001 - cell.com
Human natural killer (NK) cells comprise≈ 15% of all circulating lymphocytes. Owing to their
early production of cytokines and chemokines, and ability to lyse target cells without prior …
early production of cytokines and chemokines, and ability to lyse target cells without prior …
Human natural killer cells: a unique innate immunoregulatory role for the CD56bright subset
MA Cooper, TA Fehniger, SC Turner… - Blood, The Journal …, 2001 - ashpublications.org
During the innate immune response to infection, monocyte-derived cytokines (monokines),
stimulate natural killer (NK) cells to produce immunoregulatory cytokines that are important …
stimulate natural killer (NK) cells to produce immunoregulatory cytokines that are important …
[HTML][HTML] Human Circulating and Tissue-Resident CD56bright Natural Killer Cell Populations
JE Melsen, G Lugthart, AC Lankester… - Frontiers in …, 2016 - frontiersin.org
Two human natural killer (NK) cell subsets are usually distinguished, displaying the
CD56dimCD16+ and the CD56brightCD16−/+ phenotype. This distinction is based on NK …
CD56dimCD16+ and the CD56brightCD16−/+ phenotype. This distinction is based on NK …
Gene and protein characteristics reflect functional diversity of CD56dim and CD56bright NK cells
Recent findings underline the role of NK cell subsets in regulating adaptive immunity. To
define characteristics of NK cell subpopulations, purified CD56dim and CD56bright NK cells …
define characteristics of NK cell subpopulations, purified CD56dim and CD56bright NK cells …