Structure, enzymatic activities, glycation and therapeutic potential of human serum albumin: A natural cargo

G Rabbani, SN Ahn - International journal of biological macromolecules, 2019 - Elsevier
Human serum albumin (HSA) is an opulent, non-glycosylated, most versatile carrier protein
in plasma possessing multiple functions. HSA has the ability to interact with a variety of …

Ligand binding strategies of human serum albumin: how can the cargo be utilized?

A Varshney, P Sen, E Ahmad, M Rehan… - Chirality: The …, 2010 - Wiley Online Library
Human serum albumin (HSA), being the most abundant carrier protein in blood and a
modern day clinical tool for drug delivery, attracts high attention among biologists. Hence, its …

The extraordinary ligand binding properties of human serum albumin

M Fasano, S Curry, E Terreno, M Galliano, G Fanali… - IUBMB …, 2005 - Wiley Online Library
Human serum albumin (HSA), the most prominent protein in plasma, binds different classes
of ligands at multiple sites. HSA provides a depot for many compounds, affects …

[HTML][HTML] Serum albumin: a multifaced enzyme

G De Simone, A di Masi, P Ascenzi - International Journal of Molecular …, 2021 - mdpi.com
Human serum albumin (HSA) is the most abundant protein in plasma, contributing actively to
oncotic pressure maintenance and fluid distribution between body compartments. HSA acts …

Modifications of human serum albumin and their binding effect

P Lee, X Wu - Current pharmaceutical design, 2015 - ingentaconnect.com
Human serum albumin (HSA) regulates the transport and availability of numerous chemical
compounds and molecules in the blood vascular system. While previous HSA research has …

[HTML][HTML] Interactive association of drugs binding to human serum albumin

F Yang, Y Zhang, H Liang - International journal of molecular sciences, 2014 - mdpi.com
Human serum albumin (HSA) is an abundant plasma protein, which attracts great interest in
the pharmaceutical industry since it can bind a remarkable variety of drugs impacting their …

[HTML][HTML] Serum albumin in health and disease: esterase, antioxidant, transporting and signaling properties

DA Belinskaia, PA Voronina, VI Shmurak… - International journal of …, 2021 - mdpi.com
Being one of the main proteins in the human body and many animal species, albumin plays
a decisive role in the transport of various ions—electrically neutral and charged molecules …

Lessons from the crystallographic analysis of small molecule binding to human serum albumin

S Curry - Drug metabolism and pharmacokinetics, 2009 - jstage.jst.go.jp
Human serum albumin (HSA) is an abundant and highly soluble plasma protein with the
capacity to bind a remarkably diverse set of lipophilic anionic compounds so that it fulfils …

Novel insights into the pleiotropic effects of human serum albumin in health and disease

CE Ha, NV Bhagavan - Biochimica et Biophysica Acta (BBA)-General …, 2013 - Elsevier
Background Human serum albumin is the principal protein in human serum. It participates in
regulation of plasma oncotic pressure and transports endogenous and exogenous ligands …

Reversible and covalent binding of drugs to human serum albumin: methodological approaches and physiological relevance

C Bertucci, E Domenici - Current medicinal chemistry, 2002 - ingentaconnect.com
Human serum albumin (HSA) plays a fundamental role in the transport of drugs, metabolites,
and endogenous ligands. Binding to HSA controls the free, active concentration of a drug …