Vascular endothelial growth factors (VEGFs) regulate blood and lymphatic vessel
development through VEGF receptors (VEGFRs). The VEGFR immunoglobulin homology …

The vascular endothelial growth factor (VEGF) and its receptor (VEGFR) have been shown
to play major roles not only in physiological but also in most pathological angiogenesis …

Angiogenesis is implicated in several pathological conditions, including cancer, and in
regenerative processes, including the formation of collateral blood vessels after stroke …

VEGF is believed to be a master regulator in both developmental and pathological
angiogenesis. The role of PDGF-C in angiogenesis, however, is only at the beginning of …

Blood vessel expansion is driven by sprouting angiogenesis of endothelial cells, and is
essential for development, wound healing and disease. Membrane-localized vascular …

The platelet-derived growth factor receptor (PDGFR) family of receptor tyrosine kinases
allows cells to communicate with the environment to regulate diverse cellular activities …

The recently identified vascular endothelial growth factor C (VEGF‐C) belongs to the platelet‐
derived growth factor (PDGF)/VEGF family of growth factors and is a ligand for the …

Vascular endothelial growth factor-D (VEGF-D) is a secreted glycoprotein that promotes
growth of blood vessels (angiogenesis) and lymphatic vessels (lymphangiogenesis), and …

Combined stimulation with VEGF-A, FGF-2, or PDGF-BB has emerged as a potent strategy
for therapeutic angiogenesis, although the mechanisms underlying the synergism of these …

Abstract Vascular Endothelial Growth Factor (VEGF) signal transduction is central to
angiogenesis in development and in pathological conditions such as cancer, retinopathy …