Medial Prefrontal Cortex 5-HT2A Density Is Correlated with Amygdala Reactivity, Response Habituation, and Functional Coupling

PM Fisher, CC Meltzer, JC Price, RL Coleman… - Cerebral …, 2009 - academic.oup.com
Feedback inhibition of the amygdala via medial prefrontal cortex (mPFC) is an important
component in the regulation of complex emotional behaviors. The functional dynamics of …

Pyramidal Neurons in Rat Prefrontal Cortex Projecting to Ventral Tegmental Area and Dorsal Raphe Nucleus Express 5-HT2A Receptors

P Vázquez-Borsetti, R Cortés, F Artigas - Cerebral Cortex, 2009 - academic.oup.com
The prefrontal cortex (PFC) is involved in higher brain functions altered in schizophrenia.
Classical antipsychotics modulate cortico-limbic circuits mainly through subcortical D2 …

Serotonin2C receptor localization in GABA neurons of the rat medial prefrontal cortex: implications for understanding the neurobiology of addiction

S Liu, MJ Bubar, MF Lanfranco, GR Hillman… - Neuroscience, 2007 - Elsevier
Serotonin (5-HT) action via the 5-HT2C receptor (5-HT2CR) provides an important
modulatory influence over neurons of the prefrontal cortex (PFC), which is critically involved …

Theta burst stimulation‐induced inhibition of dorsolateral prefrontal cortex reveals hemispheric asymmetry in striatal dopamine release during a set‐shifting task–a …

JH Ko, O Monchi, A Ptito, P Bloomfield… - European Journal of …, 2008 - Wiley Online Library
The prefrontostriatal network is considered to play a key role in executive functions. Previous
neuroimaging studies have shown that executive processes tested with card‐sorting tasks …

Selective serotonin 5-HT1A receptor biased agonists elicitdistinct brain activation patterns: a pharmacoMRI study

G Becker, R Bolbos, N Costes, J Redouté… - Scientific reports, 2016 - nature.com
Abstract Serotonin 1A (5-HT1A) receptors are involved in several physiological and
pathological processes and constitute therefore an important therapeutic target. The recent …

Modulation of neuronal excitability by serotonin-NMDA interactions in prefrontal cortex

P Zhong, EY Yuen, Z Yan - Molecular and Cellular Neuroscience, 2008 - Elsevier
Both serotonin and NMDA signaling in prefrontal cortex (PFC) are implicated in mental
disorders, including depression and anxiety. To understand their potential contributions to …

Blockade of 5-HT2A receptors in the medial prefrontal cortex attenuates reinstatement of cue-elicited cocaine-seeking behavior in rats

LA Pockros, NS Pentkowski, SE Swinford… - …, 2011 - Springer
Rationale The action of serotonin (5-HT) at the 5-HT 2A receptor subtype is thought to be
involved in cocaine-seeking behavior that is motivated by exposure to drug-associated cues …

Relationship between limbic and cortical 5-HT neurotransmission and acquisition and reversal learning in a go/no-go task in rats

D Masaki, C Yokoyama, S Kinoshita, H Tsuchida… - …, 2006 - Springer
Rationale Specific brain structures have been suggested to be involved in impulsive
responding assessed by a variety of operant tasks. Central serotonin (5-HT) function has …

SNRIs achieve faster antidepressant effects than SSRIs by elevating the concentrations of dopamine in the forebrain

J Li, C Lu, Z Gao, Y Feng, H Luo, T Lu, X Sun, J Hu… - …, 2020 - Elsevier
Major depressive disorder (MDD) is a severe mental disorder with a high disability rate
worldwide. Selective serotonin reuptake inhibitors (SSRIs) and serotonin and …

[HTML][HTML] Laminar and cellular distribution of monoamine receptors in rat medial prefrontal cortex

N Santana, F Artigas - Frontiers in neuroanatomy, 2017 - frontiersin.org
The prefrontal cortex (PFC) is deeply involved in higher brain functions, many of which are
altered in psychiatric conditions. The PFC exerts a top-down control of most cortical and …