Secretion of TcpF by the Vibrio cholerae toxin-coregulated pilus biogenesis apparatus requires an N-terminal determinant

CJ Megli, RK Taylor - Journal of bacteriology, 2013 - Am Soc Microbiol
Type IV pili are important for microcolony formation, biofilm formation, twitching motility, and
attachment. We and others have shown that type IV pili are important for protein secretion …

Biogenesis and regulation of the Vibrio cholerae toxin-coregulated pilus: analogies to other virulence factor secretory systems

MR Kaufman, CE Shaw, ID Jones, RK Taylor - Gene, 1993 - Elsevier
Biogenesis of the toxin-coregulated pilus (TCP) of Vibrio cholerae 01 is essential for
successful bacterial colonization of the small intestine. Pilus assembly requires the products …

The toxin-co-regulated pilus of Vibrio cholerae 01: a model for type 4 pilus biogenesis?

JR Iredell, PA Manning - Trends in Microbiology, 1994 - Elsevier
The toxin-co-regulated pilus (TCP), an important colonization factor of Vibrio cholerae, is
similar to the type 4 pilus produced by a variety of pathogenic Gram-negative bacteria. The …

Delineation of pilin domains required for bacterial association into microcolonies and intestinal colonization by Vibrio cholerae

TJ Kirn, MJ Lafferty, CMP Sandoe… - Molecular …, 2000 - Wiley Online Library
The toxin‐co‐regulated pilus (TCP), a type 4 pilus that is expressed by epidemic strains of
Vibrio cholerae O1 and O139, is required for colonization of the human intestine. The TCP …

The toxin‐coregulated pilus: biogenesis and function

MR Kaufman, RK Taylor - Vibrio cholerae and cholera …, 1994 - Wiley Online Library
The best characterized pilus of Vibrio cholerae is the toxin‐coregulated pilus (TCP)
described by Taylor and coworkers. The pilus is designated TCP, for toxin‐coregulated …

Effects of tcpB Mutations on Biogenesis and Function of the Toxin-Coregulated Pilus, the Type IVb Pilus of Vibrio cholerae

Y Gao, CA Hauke, JM Marles, RK Taylor - Journal of Bacteriology, 2016 - Am Soc Microbiol
Vibrio cholerae is the etiological agent of the acute intestinal disorder cholera. The toxin-
coregulated pilus (TCP), a type IVb pilus, is an essential virulence factor of V. cholerae …

Secretion of a soluble colonization factor by the TCP type 4 pilus biogenesis pathway in Vibrio cholerae

TJ Kirn, N Bose, RK Taylor - Molecular microbiology, 2003 - Wiley Online Library
Colonization of the human small intestine by Vibrio cholerae requires the type 4 toxin co‐
regulated pilus (TCP). Genes encoding the structure and biogenesis functions of TCP are …

The physical basis of type 4 pilus-mediated microcolony formation by Vibrio cholerae O1

BA Jude, RK Taylor - Journal of structural biology, 2011 - Elsevier
The Vibrio cholerae toxin co-regulated pilus (TCP) is a type 4b pilus that mediates bacterial
microcolony formation, which is essential for intestinal colonization. Structural analyses have …

[HTML][HTML] Domains within the Vibrio cholerae toxin coregulated pilin subunit that mediate bacterial colonization

D Sun, MJ Lafferty, JA Peek, RK Taylor - Gene, 1997 - Elsevier
Several experimental approaches have provided evidence suggesting that a domain within
the C-terminal region of the TcpA pilin, delineated by the single disulfide loop, is directly …

Identification of a TcpC-TcpQ Outer Membrane Complex Involved in the Biogenesis of the Toxin-Coregulated Pilus of Vibrio cholerae

N Bose, RK Taylor - Journal of bacteriology, 2005 - Am Soc Microbiol
The toxin-coregulated pilus (TCP) of Vibrio cholerae and the soluble TcpF protein that is
secreted via the TCP biogenesis apparatus are essential for intestinal colonization. The TCP …