MTHFR genotypes and breast cancer survival after surgery and chemotherapy: a report from the Shanghai Breast Cancer Study
Methylenetetrahydrofolate reductase (MTHFR) regulates the intracellular folates pool for
DNA synthesis and methylation. Sequence variations in MTHFR (nucleotides 677 (C→ T) …
DNA synthesis and methylation. Sequence variations in MTHFR (nucleotides 677 (C→ T) …
Association of MTHFR gene polymorphisms with breast cancer survival
DN Martin, BJ Boersma, TM Howe, JE Goodman… - BMC cancer, 2006 - Springer
Background Two functional single nucleotide polymorphisms (SNPs) in the 5, 10-
methylenetetrahydrofolate reductase (MTHFR) gene, C677T and A1298C, lead to …
methylenetetrahydrofolate reductase (MTHFR) gene, C677T and A1298C, lead to …
MTHFR C677T polymorphism associated with breast cancer susceptibility: a meta-analysis involving 15,260 cases and 20,411 controls
J Zhang, LX Qiu, ZH Wang, XH Wu, XJ Liu… - Breast cancer research …, 2010 - Springer
Published data on the association between MTHFR C677T polymorphism and breast cancer
risk are inconclusive. To derive a more precise estimation of the relationship, a meta …
risk are inconclusive. To derive a more precise estimation of the relationship, a meta …
Polymorphisms in the MTHFR gene are associated with breast cancer
E Ergul, A Sazci, Z Utkan, NZ Canturk - Tumor biology, 2004 - karger.com
The methylenetetrahydrofolate reductase (MTHFR) gene is a polymorphic gene involved in
folate metabolism, DNA biosynthesis, methylation and genomic integrity in actively dividing …
folate metabolism, DNA biosynthesis, methylation and genomic integrity in actively dividing …
No association between methylenetetrahydrofolate reductase C677T polymorphism and breast cancer
Methylenetetrahydrofolate reductase (MTHFR) is an enzyme (EC 1.5. 1.20), that reduces 5,
10‐methylenetetrahydrofolate to 5‐methyltetrahydrofolate, a carbon donor for the …
10‐methylenetetrahydrofolate to 5‐methyltetrahydrofolate, a carbon donor for the …
The common 677C> T gene polymorphism of methylenetetrahydrofolate reductase gene is not associated with breast cancer risk
U Langsenlehner, P Krippl, W Renner… - Breast cancer research …, 2003 - Springer
Methylenetetrahydrofolate reductase (MTHFR) is involved in folate metabolism and plays a
role in DNA biosynthesis, methylation, and repair in actively dividing cells. A common 677C> …
role in DNA biosynthesis, methylation, and repair in actively dividing cells. A common 677C> …
Association of the MTHFR Gene C677T Polymorphism with Breast Cancer in a Turkish Population
EF Kaya, N Karakus, AN Ulusoy, C Özaslan… - Oncology research and …, 2016 - karger.com
Background: Breast cancer is the most common cancer among women. 1 in every 8 women
in the United States have a lifetime risk of getting breast cancer. MTHFR is a key enzyme …
in the United States have a lifetime risk of getting breast cancer. MTHFR is a key enzyme …
[PDF][PDF] Association between MTHFR 677C/T and 1298A/C gene polymorphisms and breast cancer risk
XF Zhang, T Liu, Y Li, S Li - Genet Mol Res, 2015 - funpecrp.com.br
We performed a case-control study to investigate the association between single nucleotide
polymorphisms in the MTHFR gene (677C/T and 1298A/C) and risk of breast cancer. This …
polymorphisms in the MTHFR gene (677C/T and 1298A/C) and risk of breast cancer. This …
Methylenetetrahydrofolate reductase polymorphism and susceptibility to breast cancer
Background A growing body of evidence suggests that variations in the levels of folate may
contribute to the development of cancer. A functional polymorphic variant (C→ T substitution …
contribute to the development of cancer. A functional polymorphic variant (C→ T substitution …
Association of 677 C>T (rs1801133) and 1298 A>C (rs1801131) Polymorphisms in the MTHFR Gene and Breast Cancer Susceptibility: A Meta-Analysis Based on …
K Li, W Li, X Dong - PloS one, 2014 - journals.plos.org
Objective The 677 C> T and 1298 A> C polymorphisms of methylenetetrahydrofolate
reductase (MTHFR) gene have been widely reported and considered to have a significant …
reductase (MTHFR) gene have been widely reported and considered to have a significant …