Favorable response to high-dose infliximab for refractory childhood uveitis

P Kahn, M Weiss, LF Imundo, DM Levy - Ophthalmology, 2006 - Elsevier
OBJECTIVE: Uveitis in children most commonly is associated with juvenile idiopathic
arthritis. In addition to topical glucocorticoids, treatment may include systemic …

Infliximab to treat chronic noninfectious uveitis in children: retrospective case series with long-term follow-up

SP Ardoin, D Kredich, E Rabinovich… - American journal of …, 2007 - Elsevier
PURPOSE: To assess a response to infliximab therapy in childhood uveitis. DESIGN:
Retrospective case series. METHODS: We reviewed the course of 16 children with …

Infliximab for juvenile idiopathic arthritis‐associated uveitis

JC Richards, ML Tay‐Kearney… - Clinical & …, 2005 - Wiley Online Library
Background: Infliximab is a murine–human recombinant antitumour necrosis factor
monoclonal antibody recently introduced for the treatment of autoimmune diseases in which …

Retrospective case review of pediatric patients with uveitis treated with infliximab

RT Rajaraman, Y Kimura, S Li, K Haines, DS Chu - Ophthalmology, 2006 - Elsevier
PURPOSE: To assess the response and adverse events associated with infliximab treatment
for refractory, noninfectious pediatric uveitis. DESIGN: Retrospective noncomparative case …

Loss of efficacy during long-term infliximab therapy for sight-threatening childhood uveitis

G Simonini, ME Zannin, R Caputo, F Falcini… - …, 2008 - academic.oup.com
Objective. To describe efficacy and safety of infliximab in the treatment of childhood chronic
uveitis during a long-term follow-up. Methods. Fifteen patients (median age 12 yrs, range 5 …

Retrospective analysis of children with uveitis treated with infliximab

I Tugal-Tutkun, Ö Ayranci, Ö Kasapcopur… - Journal of American …, 2008 - Elsevier
Tumor necrosis factor-alpha (TNF-α) antagonists have been successfully used in refractory
cases of pediatric uveitis. 1-7 We report our experience with the monoclonal anti-TNF-α …

Tumour necrosis factor α inhibitors in the treatment of childhood uveitis

RK Saurenmann, AV Levin, JB Rose, S Parker… - …, 2006 - academic.oup.com
Objective. To describe the efficacy of anti-TNF-α agents in the treatment of childhood uveitis.
Methods. We performed a retrospective chart review of all children with uveitis treated with …

Response of pediatric uveitis to tumor necrosis factor-α inhibitors

MA Lerman, JM Burnham, PY Chang, E Daniel… - The Journal of …, 2013 - jrheum.org
Objective. To evaluate the outcome of tumor necrosis factor-α inhibition (anti-TNF) for
pediatric uveitis. Methods. We retrospectively assessed children (age≤ 18 yrs) with …

High dose infliximab in the treatment of refractory uveitis: does dose matter?

S Sukumaran, K Marzan, B Shaham… - International Scholarly …, 2012 - Wiley Online Library
Background. Infliximab (INF) has been shown to be beneficial in treating refractory uveitis,
however, no data exist on optimal dosing and the efficacy of higher dosing. Objectives. To …

A prospective trial of infliximab therapy for refractory uveitis: preliminary safety and efficacy outcomes

EB Suhler, JR Smith, MS Wertheim… - Archives of …, 2005 - jamanetwork.com
Objective Infliximab, a monoclonal antibody against tumor necrosis factor α, is approved by
the US Food and Drug Administration for treatment of numerous autoimmune disorders. We …