Increasingly, mitochondria are being recognized as having an important role in fertility.
Indeed in assisted reproductive technologies mitochondrial function is a key indicator of …

Although the identification of specific genes that regulate apoptosis has been a topic of
intense study, little is known of the role that background genetic variance plays in …

Infertility affects around 8% of couples with a slight change in percentage in the last years.
Despite the significant efforts made in Assisted Reproductive Technologies (ARTs) in …

Primary ovarian insufficiency (POI), also known as premature ovarian failure, is a form of
hypergonadotropic hypogonadism that causes infertility in~ 1% of women< 40 years of age …

Mitochondria are the key regulators of multiple vital cellular processes, including apoptosis,
calcium homeostasis, and the generation of ATP via the metabolic pathway known as …

Primary ovarian insufficiency is one of the main causes of female infertility owing to an
abnormal ovarian reserve. Its relevance has increased in more recent years due to the fact …

Premature ovarian failure is defined as hypoestrogenism with elevated gonadotropins,
occurring before the age of 40. The prevalence of this syndrome is 3% of the women …

Fertility disorders have become a growing problem worldwide. It is well known that female
fertility decreases with age, previous studies suggested that the age-related decline in …

Embryonic development is readily compromised by imperfections introduced during the
process of oocyte maturation. We discuss the nature and causes of these imperfections …

Unusual and consistent defects in infertility patients merit attention as these may indicate an
underlying genetic abnormality, in turn necessitating tailored management strategies. We …