BACKGROUND Infertility affects between 10 and 16% of couples worldwide. Twenty to 30%
of cases of infertility are due to a male factor, 20–35% to a female factor, and 25–40% are …

The oocyte is the major determinant of embryo developmental competence in women. It
delivers half the chromosomal complement to the embryo, but the maternal and paternal …

The oocyte is a unique and highly specialized cell responsible for creating, activating, and
controlling the embryonic genome, as well as supporting basic processes such as cellular …

Primary ovarian insufficiency (POI) is a heterogeneous disease resulting from non-functional
ovaries in women before the age of 40. It is characterized by primary amenorrhea or …

Purpose The number of women attempting to conceive between the ages of 36 and 44 has
increased significantly in the last decade. While it is well established that women's …

Mitochondria are well known as 'the powerhouses of the cell'. Indeed, their major role is
cellular energy production driven by both mitochondrial and nuclear DNA. Such a feature …

Genetics of premature ovarian failure : Current Opinion in Obstetrics and Gynecology Genetics
of premature ovarian failure : Current Opinion in Obstetrics and Gynecology Log in or Register …

Since the beginning of in vitro fertilization (IVF), basic research has provided insight in the
field of human reproduction, especially in genetics. Indeed, the contribution of chromosomal …

The oocyte requires a vast supply of energy after fertilization to support critical events such
as spindle formation, chromatid separation, and cell division. Until blastocyst implantation …

Premature ovarian insufficiency (POI) is a major cause of female infertility. It is a
heterogeneous disease that affects about 1% of women under 40 years of age. POI may be …