Premature ovarian failure (POF) is a condition characterized by cessation of ovarian function
before the age of 40. The recent meeting at the National Institute of Child Health and Human …

STUDY QUESTION What part do mitochondria play in cases of diminished ovarian reserve
(DOR)? SUMMARY ANSWER Mitochondrial biogenesis in cumulus cells may be linked with …

Abstract Purpose Approximately 1–2% of the women faces three or more successive
spontaneous miscarriages termed as recurrent miscarriage (RM). Many clinical factors have …

Our research has focused on promoting the development of compromised embryos by
transferring presumably normal ooplasm, including mitochondria, to oocytes during …

Infertility can be defined as difficulty in conceiving a child after 1 year of unprotected
intercourse. Infertility can arise either because of the male factor or female factor or both …

BACKGROUND The Fifth Evian Annual Reproduction (EVAR) Workshop Meeting discussed
knowledge regarding contemporary genetics in female reproduction. METHODS Specialist …

Objectives: Correlations between parental age, aneuploidy in germ cells and recent findings
on aetiological factors in mammalian trisomy formation are reviewed. Methods: Data from …

Purpose: To evaluate the correlation between the presence of a newly described
mitochondrial DNA (mtDNA) mutation (Δ mtDNA 5286), patients' age, and in vitro fertilization …

Oocytes become enclosed in primordial follicles during fetal life and remain dormant there
until activation followed by growth and meiotic resumption. Current knowledge about the …

Mitochondrial DNA content varies considerably in oocytes, even when collected from the
same patient. In the present study, real-time quantitative polymerase chain reaction analysis …