The two primary aims of the trial are to compare the effects in hypertensive men and women
of a beta-blocker±diuretic with a calcium channel blocker±ACE inhibitor on non-fatal MI and …

Selection of the appropriate dose of a new drug for initiation of treatment and then for
maintenance is a complicated task. It requires the careful assessment and weighing of …

Background: Some antihypertensive therapies are limited by dose-dependent adverse
effects (AEs). The angiotensin II receptor blocker valsartan has been shown to reduce blood …

In an open, multicenter study, the calcium antagonist lacidipine was tested for efficacy and
safety, particularly with respect to any influence on lipid and carbohydrate metabolism. The …

Lercanidipine has demonstrated a good antihypertensive efficacy and an excellent
tolerability profile, not only in randomized clinical trials but also in daily clinical practice. With …

Role of calcium channel blockers in the future, in view of the INSIGHT Study. The data from
The International Nifedipine Intervention as a Goal in Hypertension Treatment (INSIGHT) …

DIHYDROPYRIDINE CALCIUM- CHANNELBLOCKERSFOR ANTIHYPERTENSIVE TREATMENT IN
OLDER PATIENTS - EVIDENCE FROM THE SYSTOLIC HYPERTENSI Page 1 DIHYDROPYRIDINE …

To determine whether the antihypertensive effectiveness of lercanidipine was independent
of the different cardiovascular risk levels. Patients with treated or untreated mild‐to …

Systemic hypertension is a major global problem contributing to enormous disease burden,
premature morbidity and mortality. A substantial majority of hypertensive patients require …

The second half of the 20th century has seen a constant de-crease in cardiovascular
mortality in the Western industrialised nations [1]. This decrease has occurred concomitantly …