Two major autoantibody clusters in systemic lupus erythematosus

KH Ching, PD Burbelo, C Tipton, C Wei, M Petri, I Sanz… - PloS one, 2012 - journals.plos.org
Systemic lupus erythematosus is a chronic autoimmune disease of complex clinical
presentation and etiology and is likely influenced by numerous genetic and environmental …

Autoantibodies in systemic lupus erythematosus: comparison of historical and current assessment of seropositivity

A Ippolito, DJ Wallace, D Gladman, PR Fortin… - Lupus, 2011 - journals.sagepub.com
Systemic lupus erythematosus (SLE) is characterized by multiple autoantibodies and
complement activation. Recent studies have suggested that anti-nuclear antibody (ANA) …

Specific antinuclear antibodies are associated with clinical features in systemic lupus erythematosus

IEA Hoffman, I Peene, L Meheus… - Annals of the …, 2004 - ard.bmj.com
Objectives: To study associations between antinuclear antibodies (ANA) and
signs/symptoms in patients with systemic lupus erythematosus (SLE). Methods: A …

Comparison of autoantibody specificities between traditional and bead‐based assays in a large, diverse collection of patients with systemic lupus erythematosus and …

BF Bruner, JM Guthridge, R Lu, G Vidal… - Arthritis & …, 2012 - Wiley Online Library
Objective Replacement of standard immunofluorescence methods with bead‐based assays
for antinuclear antibody (ANA) testing is a new clinical option. The aim of this study was to …

Multiparametric detection of autoantibodies in systemic lupus erythematosus

P Budde, HD Zucht, S Vordenbäumen, H Goehler… - Lupus, 2016 - journals.sagepub.com
Systemic lupus erythematosus (SLE) is a heterogeneous disease with respect to disease
manifestations, disease progression and treatment response. Therefore, strategies to …

Cluster analysis of autoantibodies in 852 patients with systemic lupus erythematosus from a single center

B Artim-Esen, E Çene, Y Şahinkaya, S Ertan… - The Journal of …, 2014 - jrheum.org
Objective. Associations between autoantibodies and clinical features have been described
in systemic lupus erythematosus (SLE). Herein, we aimed to define autoantibody clusters …

Autoantibodies to ribonucleoproteins

JA Hardin, T Mimori - Clinics in rheumatic diseases, 1985 - Elsevier
Presently we recognize at least 12 different autoantibodies that involve ribonucleoproteins
as antigens in patients with SLE and other rheumatic diseases. Such autoantibodies have a …

Rare autoantibodies to cellular antigens in systemic lupus erythematosus

M Fredi, I Cavazzana, M Quinzanini, M Taraborelli… - Lupus, 2014 - journals.sagepub.com
Objective A high number of antinuclear antibody specificities can be detected in systemic
lupus erythematosus (SLE). Some of them are related to a distinct clinical subset of disease …

Autoantibodies in systemic lupus erythematosus: From immunopathology to therapeutic target

H Lou, GS Ling, X Cao - Journal of autoimmunity, 2022 - Elsevier
Systemic lupus erythematosus (SLE) is an autoimmune disease characterized by multiple
organ inflammatory damage and wide spectrum of autoantibodies. The autoantibodies …

Systemic lupus erythematosus one disease or many?

N Agmon-Levin, M Mosca, M Petri, Y Shoenfeld - Autoimmunity reviews, 2012 - Elsevier
Systemic lupus erythematosus (SLE) characterizes by a variety of clinical manifestations and
the presence of a wide profile of autoantibodies. This clinical and serological heterogeneity …