The widespread use of whole-cell pertussis vaccines in the second half of the 20th century
have reduced the incidence of the disease significantly. However, in some countries …

A tricomponent acellular pertussis vaccine containing pertussis toxoid, filamentous
hemagglutinin, and pertactin combined with diphtheria and tetanus toxoids (DTPa) was …

Effective diphtheria, tetanus toxoids, whole-cell pertussis (wP) vaccines were used for
massive immunization in the 1950s. The broad use of these vaccines significantly reduced …

A single blinded randomized controlled trial to compare the reactogenicity and
immunogenicity of adult formulated dTpa and monovalent pa vaccines with a licensed Td …

Available data relating to pertussis and pertussis immunization are frequently overlooked or
misinterpreted. Mortality due to pertussis is underreported. Most whole cell pertussis …

Two clinical studies were undertaken to evaluate the immunogenicity of an adult-type dTpa
booster vaccine (Boostrix™ by GlaxoSmithKline Biologicals). Blood samples taken prior to …

Background Concern about both safety and efficacy has made the use of whole-cell
pertussis vaccines controversial. In some European countries, including Italy, the rate of …

Diphtheria-tetanus-acellular pertussis vaccines have been licensed in the United States
since 1991. Compared with the whole cell pertussis component diphtheria-tetanus-pertussis …

We compared immunogenicity and reactogenicity of a single dose of DTaP vaccine
(containing tetanus and diphtheria toxoids and four acellular pertussis antigens) with …

The aim of this assessor-blinded trial was to compare the immunogenicity and reactogenicity
of a candidate diphtheria, tetanus toxoids and acellular pertussis vaccine with reduced …