Acute myeloid leukemia: from mutation profiling to treatment decisions
C DiNardo, C Lachowiez - Current hematologic malignancy reports, 2019 - Springer
Abstract Purpose of Review Awareness of the molecular landscape of AML has improved
AML care over the last 5 years. This review summarizes updates regarding the diagnostic …
AML care over the last 5 years. This review summarizes updates regarding the diagnostic …
The evolving molecular genetic landscape in acute myeloid leukaemia
MA Sanders, PJM Valk - Current opinion in hematology, 2013 - journals.lww.com
The list of acquired mutations with clinical value in AML is growing. Clinical implementation
of this multitude of markers will require integrated approaches and selection of markers to …
of this multitude of markers will require integrated approaches and selection of markers to …
Molecular therapy for acute myeloid leukaemia
CC Coombs, MS Tallman, RL Levine - Nature reviews Clinical oncology, 2016 - nature.com
Acute myeloid leukaemia (AML) is a heterogeneous disease that is, in general, associated
with a very poor prognosis. Multiple cytogenetic and molecular abnormalities that …
with a very poor prognosis. Multiple cytogenetic and molecular abnormalities that …
Acute myeloid leukemia: biologic, prognostic, and therapeutic insights
S Khaled, M Al Malki, G Marcucci - Oncology, 2016 - go.gale.com
Acute myeloid leukemia (AML) is a biologically complex and molecularly and clinically
heterogeneous disease, and its incidence is increasing as the population ages …
heterogeneous disease, and its incidence is increasing as the population ages …
[HTML][HTML] The clinical impact of the molecular landscape of acute myeloid leukemia
S Kayser, MJ Levis - Haematologica, 2023 - ncbi.nlm.nih.gov
Research into the underlying pathogenic mechanisms of acute myeloid leukemia (AML) has
led to remarkable advances in our understanding of the disease. Mutations now allow us to …
led to remarkable advances in our understanding of the disease. Mutations now allow us to …
[HTML][HTML] Molecular landscape of acute myeloid leukemia: prognostic and therapeutic implications
L Marando, BJP Huntly - Current oncology reports, 2020 - Springer
Abstract Purpose of Review The field of acute myeloid leukemia (AML) has been
revolutionized in recent years by the advent of high-throughput techniques, such as next …
revolutionized in recent years by the advent of high-throughput techniques, such as next …
How do novel molecular genetic markers influence treatment decisions in acute myeloid leukemia?
JP Patel, RL Levine - Hematology 2010, the American Society …, 2012 - ashpublications.org
Acute myeloid leukemia (AML) is the most common acute leukemia diagnosed in adults, and
the majority of patients with AML die from relapsed disease. Although many studies over the …
the majority of patients with AML die from relapsed disease. Although many studies over the …
Acute myeloid leukaemia
A Khwaja, M Bjorkholm, RE Gale, RL Levine… - Nature reviews Disease …, 2016 - nature.com
Acute myeloid leukaemia (AML) is a disorder characterized by a clonal proliferation derived
from primitive haematopoietic stem cells or progenitor cells. Abnormal differentiation of …
from primitive haematopoietic stem cells or progenitor cells. Abnormal differentiation of …
[HTML][HTML] Gene mutations of acute myeloid leukemia in the genome era
T Naoe, H Kiyoi - International journal of hematology, 2013 - Springer
Ten years ago, gene mutations found in acute myeloid leukemia (AML) were conceptually
grouped into class I mutation, which causes constitutive activation of intracellular signals that …
grouped into class I mutation, which causes constitutive activation of intracellular signals that …
Molecular characterization of acute myeloid leukemia and its impact on treatment
O Frankfurt, JD Licht, MS Tallman - Current opinion in Oncology, 2007 - journals.lww.com
Molecular characterization of acute myeloid leukemia and its... : Current Opinion in Oncology
Molecular characterization of acute myeloid leukemia and its impact on treatment : Current …
Molecular characterization of acute myeloid leukemia and its impact on treatment : Current …