Abstract The compound (±)-trans-4-hydroxy-6-propyl-1-oxocyclohexan-2-one [(±)-δ-lactone]
was isolated from the plant Vitex cymosa Bertero, and determined to be the active principle …

The objective of this study was to investigate spinal and supraspinal antinociceptive effects
of a new synthetic compound,(±)-cis-(6-ethyl-tetrahydropyran-2-yl)-formic acid …

Pain is a major cause of distress, both physical and psychological. There is a continuous
search for new pharmacologically active analgesic agents with minor adverse effects …

The effects of enantiomorphs of TAN-67 (2-methyl-4 a α-(3-hydroxyphenyl)-1, 2, 3, 4, 4a, 5,
12, 12aα-octahydro-quinolino [2, 3, 3-g] isoquinoline),(−) TAN-67 and (+) TAN-67, given …

The present study investigated the possible involvement of the glutamatergic and neurokinin
systems in the antinociception caused by triterpene 3β, 6β, 16β-trihydroxylup-20 (29)-ene …

In the present study, we describe the antinociceptive effect of filicene, a triterpene isolated
from Adiantumcuneatum (Adiantaceae) leaves, in several models of pain in mice. When …

A series of studies performed in our laboratory have shown that (−)-linalool, the natural
occurring enantiomer in essential oils, possesses anti-inflammatory and antinociceptive …

The present study investigated the mechanisms involved in the antinociception produced by
the triterpene 3β, 6β, 16β-trihydroxylup-20 (29)-ene (TTHL) in mice. TTHL administered by …

The effect of a leukotriene D4 receptor antagonist,(3-(3-(2-(7-chloro-2-quinolinyl) ethenyl)
phenyl (3-dimethyl amino-3-oxo propyl) thio) methyl) thio) propanoic acid (L-660,711; MK …

We used multiple pain models to investigate the effects of (-)-linalool, a monoterpene
alcohol present in the essential oil of plants, on chronic inflammatory and neuropathic …