Integrated multifunctional electrochemistry microchip for highly efficient capture, release, lysis, and analysis of circulating tumor cells

S Yan, P Chen, X Zeng, X Zhang, Y Li, Y Xia… - Analytical …, 2017 - ACS Publications
The circulating tumor cells (CTCs) in the blood allow the noninvasive analysis of metastatic
mechanisms, cancer diagnosis, prognosis, disease monitoring, and precise therapy through …

A three-dimensional conductive scaffold microchip for effective capture and recovery of circulating tumor cells with high purity

SB Cheng, MM Chen, YK Wang, ZH Sun, Y Qin… - Analytical …, 2021 - ACS Publications
Effective acquirement of highly pure circulating tumor cells (CTCs) is very important for CTC-
related research. However, it is a great challenge since abundant white blood cells (WBCs) …

Cancer cell analyses at the single cell-level using electroactive microwell array device

M Kobayashi, SH Kim, H Nakamura, S Kaneda, T Fujii - PloS one, 2015 - journals.plos.org
Circulating tumor cells (CTCs), shed from primary tumors and disseminated into peripheral
blood, are playing a major role in metastasis. Even after isolation of CTCs from blood, the …

In situ electrochemical ELISA for specific identification of captured cancer cells

TS Safaei, RM Mohamadi, EH Sargent… - ACS applied materials …, 2015 - ACS Publications
Circulating tumor cells (CTCs) are cancer cells disseminated from a tumor into the
bloodstream. Their presence in patient blood samples has been associated with metastatic …

Micro/nanofluidic-electrochemical biosensors for in situ tumor cell analysis

J Han, S Liu, Z Wang, Y Wu - TrAC Trends in Analytical Chemistry, 2022 - Elsevier
Micro/nanofluidics have been demonstrated as exciting avenues for efficient capture and in
situ analysis of tumor cells, which is of great importance for early tumor diagnosis, staging …

A micro-/nano-chip and quantum dots-based 3D cytosensor for quantitative analysis of circulating tumor cells

X Wu, T Xiao, Z Luo, R He, Y Cao, Z Guo… - Journal of …, 2018 - Springer
Background Due to the high transfer ability of cancer cell, cancer has been regarded as a
world-wide high mortality disease. Quantitative analysis of circulating tumor cells (CTCs) can …

Electrochemical biosensor for cancer cell detection based on a surface 3D micro-array

L An, G Wang, Y Han, T Li, P Jin, S Liu - Lab on a Chip, 2018 - pubs.rsc.org
The detection of rare circulating tumour cells (CTCs) in patients' blood is crucial for the early
diagnosis of cancer, highly precise cancer therapy and monitoring therapeutic outcomes in …

Nanostructure embedded microchips for detection, isolation, and characterization of circulating tumor cells

M Lin, JF Chen, YT Lu, Y Zhang, J Song… - Accounts of chemical …, 2014 - ACS Publications
Conspectus Circulating tumor cells (CTCs) are cancer cells that break away from either a
primary tumor or a metastatic site and circulate in the peripheral blood as the cellular origin …

Fabrication of Channeled and Three-Dimensional Electrodes for the Integrated Capture and Detection of Invasive Circulating Tumor Cells during Hematogenous …

X Wang, T Gao, J Zhu, S Long, S Zhao, L Yuan… - Analytical …, 2023 - ACS Publications
Hematogenous metastasis is the main route of cancer spreading, causing majority death of
cancer patients. During this process, platelets in the blood are found increasingly essential …

Chip-based nanostructured sensors enable accurate identification and classification of circulating tumor cells in prostate cancer patient blood samples

I Ivanov, J Stojcic, A Stanimirovic, E Sargent… - Analytical …, 2013 - ACS Publications
The identification and analysis of circulating tumor cells (CTCs) is an important goal for the
development of noninvasive cancer diagnosis. Here we describe a chip-based method …