Doubly selective multiple quantum chemical shift imaging and T1 relaxation time measurement of glutathione (GSH) in the human brain in vivo
Mapping of a major antioxidant, glutathione (GSH), was achieved in the human brain in vivo
using a doubly‐selective multiple quantum filtering based chemical shift imaging (CSI) of …
using a doubly‐selective multiple quantum filtering based chemical shift imaging (CSI) of …
Measurement of glutathione in human brain at 3T using an improved double quantum filter in vivo
C Choi, C Zhao, I Dimitrov, D Douglas… - Journal of Magnetic …, 2009 - Elsevier
A single voxel proton NMR double quantum filter (DQF) for measurement of glutathione
(GSH) in human brain at 3T is reported. Yield enhancement for the CH2 resonances of the …
(GSH) in human brain at 3T is reported. Yield enhancement for the CH2 resonances of the …
Quantification of glutathione transverse relaxation time T2 using echo time extension with variable refocusing selectivity and symmetry in the human brain at 7 Tesla
KM Swanberg, H Prinsen, D Coman… - Journal of Magnetic …, 2018 - Elsevier
Glutathione (GSH) is an endogenous antioxidant implicated in numerous biological
processes, including those associated with multiple sclerosis, aging, and cancer. Spectral …
processes, including those associated with multiple sclerosis, aging, and cancer. Spectral …
Measurement of glutathione in normal volunteers and stroke patients at 3T using J‐difference spectroscopy with minimized subtraction errors
L An, Y Zhang, DM Thomasson… - Journal of Magnetic …, 2009 - Wiley Online Library
Purpose To develop and optimize a 1H magnetic resonance spectroscopy (MRS) method for
measuring brain glutathione (GSH) levels. Materials and Methods Phantom experiments …
measuring brain glutathione (GSH) levels. Materials and Methods Phantom experiments …
New double quantum coherence filter for localized detection of glutathione in vivo
T Zhao, K Heberlein, C Jonas… - … in Medicine: An …, 2006 - Wiley Online Library
In this work, a new double quantum filter for glutathione (GSH) editing is introduced,
combined with the point‐resolved spectroscopy localization sequence (PRESS), and …
combined with the point‐resolved spectroscopy localization sequence (PRESS), and …
Measurement of reduced glutathione (GSH) in human brain using LCModel analysis of difference‐edited spectra
M Terpstra, PG Henry, R Gruetter - Magnetic Resonance in …, 2003 - Wiley Online Library
The concentration of reduced glutathione (GSH), an antioxidant, may be altered in various
brain diseases. MEGA‐PRESS was used to edit for the 1H NMR signal from GSH in the …
brain diseases. MEGA‐PRESS was used to edit for the 1H NMR signal from GSH in the …
Non-invasive imaging of the levels and effects of glutathione on the redox status of mouse brain using electron paramagnetic resonance imaging
MC Emoto, Y Matsuoka, K Yamada… - Biochemical and …, 2017 - Elsevier
Glutathione (GSH) is the most abundant non-protein thiol that buffers reactive oxygen
species in the brain. GSH does not reduce nitroxides directly, but in the presence of …
species in the brain. GSH does not reduce nitroxides directly, but in the presence of …
MR spectroscopic imaging of glutathione in the white and gray matter at 7 T with an application to multiple sclerosis
R Srinivasan, H Ratiney… - Magnetic resonance …, 2010 - Elsevier
Detection of glutathione (GSH) is technically challenging at clinical field strengths of 1.5 or 3
T due to its low concentration in the human brain coupled with the fact that conventional …
T due to its low concentration in the human brain coupled with the fact that conventional …
In vivo brain GSH: MRS methods and clinical applications
F Bottino, M Lucignani, A Napolitano, F Dellepiane… - Antioxidants, 2021 - mdpi.com
Glutathione (GSH) is an important antioxidant implicated in several physiological functions,
including the oxidation− reduction reaction balance and brain antioxidant defense against …
including the oxidation− reduction reaction balance and brain antioxidant defense against …
Detection of glutathione in the human brain in vivo by means of double quantum coherence filtering
AH Trabesinger, OM Weber, CO Duc… - … in Medicine: An …, 1999 - Wiley Online Library
The feasibility of selective in vivo detection of glutathione (l‐γ‐glutamyl‐l‐cysteinyl‐glycine,
GSH) in the human brain by means of 1H magnetic resonance spectroscopy (MRS) at 1.5 T …
GSH) in the human brain by means of 1H magnetic resonance spectroscopy (MRS) at 1.5 T …
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