On display: autotransporter secretion and application
P Van Ulsen, KM Zinner, WSP Jong… - FEMS microbiology …, 2018 - academic.oup.com
The classical monomeric autotransporters are ubiquitously used by Gram-negative bacteria
to export virulence and colonization factors to their cell surface or into their surroundings …
to export virulence and colonization factors to their cell surface or into their surroundings …
[HTML][HTML] Autotransporter secretion: varying on a theme
Autotransporters are widely distributed among Gram-negative bacteria. They can have a
large variety of functions and many of them have a role in virulence. They are synthesized as …
large variety of functions and many of them have a role in virulence. They are synthesized as …
Overproducing the BAM complex improves secretion of difficult-to-secrete recombinant autotransporter chimeras
Monomeric autotransporters have been used extensively to transport recombinant proteins
or protein domains to the cell surface of Gram-negative bacteria amongst others for antigen …
or protein domains to the cell surface of Gram-negative bacteria amongst others for antigen …
Comparing autotransporter β-domain configurations for their capacity to secrete heterologous proteins to the cell surface
WSP Jong, M Schillemans, CM ten Hagen-Jongman… - PLoS …, 2018 - journals.plos.org
Monomeric autotransporters have been extensively used for export of recombinant proteins
to the cell surface of Gram-negative bacteria. A bottleneck in the biosynthesis of such …
to the cell surface of Gram-negative bacteria. A bottleneck in the biosynthesis of such …
Autotransporter-based cell surface display in Gram-negative bacteria
T Nicolay, J Vanderleyden… - Critical reviews in …, 2015 - Taylor & Francis
Cell surface display of proteins can be used for several biotechnological applications such
as the screening of protein libraries, whole cell biocatalysis and live vaccine development …
as the screening of protein libraries, whole cell biocatalysis and live vaccine development …
A structurally informed autotransporter platform for efficient heterologous protein secretion and display
WSP Jong, Z Soprova, K de Punder… - Microbial cell …, 2012 - Springer
Background The self-sufficient autotransporter (AT) pathway, ubiquitous in Gram-negative
bacteria, combines a relatively simple protein secretion mechanism with a high transport …
bacteria, combines a relatively simple protein secretion mechanism with a high transport …
Protein secretion in gram-negative bacteria via the autotransporter pathway
N Dautin, HD Bernstein - Annu. Rev. Microbiol., 2007 - annualreviews.org
Autotransporters are a large and diverse superfamily of proteins produced by pathogenic
gram-negative bacteria that are composed of an N-terminal passenger domain, which …
gram-negative bacteria that are composed of an N-terminal passenger domain, which …
BamA is required for autotransporter secretion
Abstract Background In Gram-negative bacteria, type Va and Vc autotransporters are
proteins that contain both a secreted virulence factor (the “passenger” domain) and a β …
proteins that contain both a secreted virulence factor (the “passenger” domain) and a β …
From self sufficiency to dependence: mechanisms and factors important for autotransporter biogenesis
DL Leyton, AE Rossiter, IR Henderson - Nature Reviews Microbiology, 2012 - nature.com
Autotransporters are a superfamily of proteins that use the type V secretion pathway for their
delivery to the surface of Gram-negative bacteria. At first glance, autotransporters look to …
delivery to the surface of Gram-negative bacteria. At first glance, autotransporters look to …
Surface display of proteins by Gram-negative bacterial autotransporters
N Rutherford, M Mourez - Microbial cell factories, 2006 - Springer
Expressing proteins of interest as fusions to proteins of the bacterial envelope is a powerful
technique with many biotechnological and medical applications. Autotransporters have …
technique with many biotechnological and medical applications. Autotransporters have …