The history of breast cancer screening is littered with controversy. With 10 trials spanning 4
decades, we have a substantial body of evidence, but with different aims and flaws …

Screening for breast cancer has been evaluated by 9 randomized trials over 5 decades and
recommended by major guideline groups for more than 3 decades. Successes and lessons …

Importance Patients need to consider both benefits and harms of breast cancer screening.
Objective To systematically synthesize available evidence on the association of …

Objectives When estimating the decline in breast cancer mortality attributable to screening,
the challenge is to provide valid comparison groups and to distinguish the screening effect …

Background: This systematic review is an update of the evidence since the 2001 Canadian
Task Force recommendations on breast cancer screening. Purpose: A decision was made to …

Breast cancer has been increasing at an alarming rate and is considered to be of epidemic
proportions in the United States, with current estimates indicating that 1 in 8 women will …

Breast cancer is a leading cause of cancer and death from cancer among women in the
developed and developing world. Detecting and treating breast cancer earlier in its natural …

Purpose Randomized, controlled trials showed that screening reduces breast cancer
mortality rates, but some recent observational studies have concluded that programmatic …

Despite strong epidemiologic evidence that screening for breast cancer with mammography
and clinical breast examination results in mortality reductions, and the considerable effort to …

Background: With changes in diagnosis, treatment, and management of breast cancer since
the mammography screening trials, there is a need to evaluate contemporary breast …