Background: Environmental contamination by fluorinated chemicals, in particular chemicals
from the per-and polyfluoroalkyl substances (PFAS) class, has raised concerns around the …

In this review, we provide a comprehensive and critical perspective on the synthesis and
application of 1, 1, 2, 2‐tetrafluoroethyl‐and tetrafluoroethylene‐containing compounds …

Per-and polyfluoroalkyl substances (PFAS) represent a versatile group of ubiquitously
occurring chemicals of increasing regulatory concern. The past years lead to an ever …

Nature has hardly evolved a biochemistry of fluorine although there is a low-level
occurrence of fluoroacetate found in selected tropical and subtropical plants. This …

Creating new insecticide lead compounds based on the design and modification of natural
products is a novel process, of which chlorfenapyr is a typical successful example …

BACKROUND: Fipronil is an insecticidal pyrazole that is commonly used as an insecticide in
field crops, urban pesticide and veterinary medicine, but there are no reports of its …

This document reviews the environmental fate and environmental effects of fipronil (5-amino-
1-[2, 6-dichloro-4-(trifluromethyl) phenyl]-4-[(trifluromethyl) sulfinyl]-1H-pyrazole). Fipronil …

Fluorine, one of the most abundant elements found on earth, acts as an environmental
xenobiotics even at sparingly low concentrations. Uncontrolled anthropogenic activities …

Organic fluorinated compounds have been detected in various environmental media and
biota. Some of these compounds are regulated locally (eg, perfluorononanoic acid …

The extraordinary potential of fluorine-containing molecules in medicinal chemistry and
chemical biology has been recognized by researchers outside of the traditional fluorine …