The macula densa detects changes in NaCl concentration in tubular fluid and transmits a
feedback signal, known as tubuloglomerular feedback (TGF), which helps to control …

Superoxide enhances tubuloglomerular feedback by constricting the afferent arteriole.
Background Superoxide (O 2−) has been shown to augment tubuloglomerular feedback …

Superoxide (O2−) enhances tubuloglomerular feedback by scavenging nitric oxide at the
macula densa. However, the singling pathway of O2− production in the macula densa is not …

Role of neuronal nitric oxide synthase in the macula densa. Background There is evidence
that macula densa nitric oxide (NO) inhibits tubuloglomerular feedback (TGF). However, TGF …

Increased intracellular pH at the macula densa activates nNOS during tubuloglomerular
feedback. Background The macula densa senses increasing NaCl concentrations in tubular …

Role of macula densa nitric oxide and cGMP in the regulation of tubuloglomerular feedback.
Background Previous studies have suggested that nitric oxide (NO) produced within cells of …

Aim Tubuloglomerular feedback (TGF) is an important mechanism in control of signal
nephron glomerular filtration rate. The oxidative stress in the macula densa, primarily …

Macula densa (MD)-mediated regulation of renal hemodynamics via tubuloglomerular
feedback is regulated by interactions between factors such as superoxide (O2−) and …

Tubuloglomerular feedback (TGF)-mediated constriction of the afferent arteriole is
modulated by a balance between release of superoxide (O2−) and nitric oxide (NO) in …

Oxidative stress implies an increased production of reactive oxygen species (ROS) or a
decreased capacity to metabolize them. Superoxide anion (O) can bioinactivate nitric oxide …