The central nervous system (CNS) is now known to actively communicate with the immune
system to control immune responses both centrally and peripherally. Within the CNS, while …

The concept of central nervous system (CNS) inflammation has evolved over the last
decades. Neuroinflammation is the response of reactive CNS components to altered …

Neuroinflammation in the central nervous system (CNS) is an important subject of
neuroimmunological research. Emerging evidence suggests that neuroinflammation is a key …

Neurodegenerative diseases, the leading cause of morbidity and disability, are gaining
increased attention as they impose a considerable socioeconomic impact, due in part to the …

The immune system's role is much more than merely recognizing self vs. non-self and
involves maintaining homeostasis and integrity of the organism starting from early …

Immune cells infiltrate the CNS in many neurological diseases with a primary or secondary
inflammatory component. In the CNS, immune cells employ shared mediators to promote …

Neuroinflammation is the response of the central nervous system (CNS) to disturbed
homeostasis and typifies all neurological diseases. The main reactive components of the …

The brain constitutes an environment that is specifically designed to accommodate, regulate
and shape immune responses. On one hand, the central nervous system (CNS) has …

Immune responses in the CNS are common, despite its perception as a site of immune
privilege. These responses can be mediated by resident microglia and astrocytes, which are …

Brain morphology and function are susceptible to various psysiological influences, including
changes in the immune system. Inflammation and autoimmunity are two principal …