In recent years, there has been increasing evidence that soluble mediators such as
cytokines from activated T lymphocytes and macrophages are able to modulate the growth …

Neurodegenerative diseases are the result of progressive loss of neurons and axons in the
central nervous system (CNS), which can lead to cognition and motor dysfunction. It is well …

Neuroinflammation was once a clearly defined term denoting pathological immune
processes within the central nervous system (CNS). Historically, this term was used to …

Neurodegeneration, the slow and progressive dysfunction and loss of neurons and axons in
the central nervous system, is the primary pathological feature of acute and chronic …

The blood-brain barrier (BBB) is not simply a physical barrier but a regulatory interface
between the central nervous system (CNS) and immune system. The BBB both affects and is …

Recent discoveries suggest that the resident cells of the central nervous system (CNS) the
nerve cells and glia, play a more immunologically active role than was previously assumed …

Neuroinflammation is a key component of neurological disorders and is an important
therapeutic target; however, immunotherapies have been largely unsuccessful. In cases …

The central nervous system (CNS) has traditionally been considered to be immunologically
privileged, but over the years there has been a re-evaluation of this dogma. To date, studies …

Over the past decades, our view on neurodegenerative diseases has been mainly centered
around neurons and their networks. Only recently it became evident that immunological …

There is an increasing recognition that inflammation plays a critical role in
neurodegenerative diseases of the CNS, including Alzheimer's disease, amyotrophic lateral …