Background: The rising incidence of pertussis amongst adults and adolescents in
industrialised countries could be reduced by replacing tetanus and diphtheria (Td) boosters …

Persistence of antibodies following a single dose of Tdap vaccine (tetanus, diphtheria, and
five-component acellular pertussis vaccine for use in individuals past childhood) was …

Background Reduced-antigen-content tetanus, diphtheria, and acellular pertussis (Tdap)
vaccine is recommended in many countries for boosting immunity in adolescents and adults …

Background In a prospective, randomized pivotal phase III clinical trial, the immunogenicity
and reactogenicity of a tetanus-diphtheria-acellular pertussis vaccine (Tdap) and a tetanus …

Abstract▴ The reduced-antigen combined diphtheria-tetanus-acellular pertussis vaccine
(dTpa) is intended for use as a booster dose in individuals aged≥ 4 years.▴ A single dose …

Introduction: Older children and adults, susceptible to pertussis because of waning
immunity, may serve as a reservoir of infection, leading to severe disease among young …

Background. Booster vaccination against tetanus and diphtheria at 10-year intervals is
commonly recommended. Reduced antigen content diphtheria and tetanus toxoids and …

BACKGROUND: Increasing incidence of pertussis in adolescents and adults has stimulated
the development of safe and immunogenic acellular pertussis vaccines for booster …

Background. The recent introduction of acellular pertussis vaccines (Pa) offers the possibility
of booster doses in older children and adults. This can be conveniently accomplished by …

OBJECTIVE: The safety of a booster dose of a reduced-antigen-content tetanus–diphtheria–
acellular pertussis (Tdap) vaccine was evaluated in adolescents previously vaccinated with …