BACKGROUND. The incidence of pertussis is increasing, especially in adolescents,
attributed in part to waning of immunity after childhood immunization. Recently licensed in …

OBJECTIVE: To estimate the contribution of whole-cell pertussis vaccine to severe local
reactions after the preschool (fifth) dose of adsorbed diphtheria toxoid-pertussis vaccine …

To measure the clinical effect of adding a whole cell pertussis component to diphtherial
tetanus vaccine (DT) given as a pre-school booster, 190 children aged 4–5 years were …

Pertussis is a vaccine preventable respiratory infection. Young infants are at high risk of
developing severe complications from infection. Despite high rates of pediatric vaccine …

235 healthy 10–12 years old school children were randomly immunized with either a
booster dose of diphtheria-tetanus-acellular pertussis (dTap) or diphtheria-tetanus (dT) …

Despite a high vaccine coverage, pertussis has re-emerged and has become the most
prevalent vaccine preventable disease in developed countries. The re-emergence of …

Longitudinal serum samples were collected from 542 children that had participated in a
Swedish pertussis vaccine trial 1992–1995 [Gustafsson L, Hallander HO, Olin P …

Background Recombinant pertussis vaccines inducing long-lasting immune responses
could help to control the rise in pertussis. We here report on persisting antibody responses 2 …

Background: Adult formulation tetanus and diphtheria toxoids and acellular pertussis
vaccines (Tdap) have been developed to prevent pertussis in adolescents and adults. There …

Objective To assess the effectiveness of reduced acellular pertussis (Tdap) vaccines in
adolescents and adults. Setting Kaiser Permanente Northern California. Design Case …