The Shc-related adaptor protein, Sck, forms a complex with the vascular-endothelial-growth-factor receptor KDR in transfected cells
AJ WARNER, J LOPEZ-DEE, EL KNIGHT… - Biochemical …, 2000 - portlandpress.com
Despite much progress in recent years, the precise signalling events triggered by the
vascular-endothelial-growth-factor (VEGF) receptors, fms-like tyrosine kinase (Flt1) and …
vascular-endothelial-growth-factor (VEGF) receptors, fms-like tyrosine kinase (Flt1) and …
[HTML][HTML] The adaptor protein shb binds to tyrosine 1175 in vascular endothelial growth factor (VEGF) receptor-2 and regulates VEGF-dependent cellular migration
K Holmqvist, MJ Cross, C Rolny, R Hägerkvist… - Journal of Biological …, 2004 - ASBMB
Previous studies have shown that the adaptor protein Shb is involved in receptor tyrosine
kinase signaling. In this study, we demonstrate that Shb is phosphorylated in an Src …
kinase signaling. In this study, we demonstrate that Shb is phosphorylated in an Src …
[HTML][HTML] Vascular endothelial cell growth factor promotes tyrosine phosphorylation of mediators of signal transduction that contain SH2 domains: association with …
D Guo, Q Jia, HY Song, RS Warren… - Journal of Biological …, 1995 - ASBMB
Vascular endothelial cell growth factor (VEGF), an endothelial cell-specific mitogen that
plays an important role in angiogenesis, promotes the tyrosine phosphorylation of at least 11 …
plays an important role in angiogenesis, promotes the tyrosine phosphorylation of at least 11 …
[HTML][HTML] The vascular endothelial growth factor receptor KDR activates multiple signal transduction pathways in porcine aortic endothelial cells
J Kroll, J Waltenberger - Journal of Biological Chemistry, 1997 - ASBMB
Vascular endothelial growth factor A (here referred to as VEGF) is an endothelium-specific
growth factor that binds to two distinct receptor tyrosine kinases, designated Flt-1 and …
growth factor that binds to two distinct receptor tyrosine kinases, designated Flt-1 and …
Sck interacts with KDR and Flt-1 via its SH2 domain
K Igarashi, K Shigeta, T Isohara, T Yamano… - … and biophysical research …, 1998 - Elsevier
Vascular endothelial growth factor (VEGF) is one of the major angiogenesis regulators. It
binds to its tyrosine kinase receptors, KDR and Flt-1. However, little is known about their …
binds to its tyrosine kinase receptors, KDR and Flt-1. However, little is known about their …
[HTML][HTML] Fibroblast growth factor receptor-1-mediated endothelial cell proliferation is dependent on the Src homology (SH) 2/SH3 domain-containing adaptor protein …
H Larsson, P Klint, E Landgren… - Journal of Biological …, 1999 - ASBMB
Stimulation of fibroblast growth factor receptor-1 (FGFR-1) expressed on endothelial cells
leads to cellular migration and proliferation. We have examined the role of the Src homology …
leads to cellular migration and proliferation. We have examined the role of the Src homology …
Sck is expressed in endothelial cells and participates in vascular endothelial growth factor-induced signaling
KE Ratcliffe, Q Tao, B Yavuz, KV Stoletov, SC Spring… - Oncogene, 2002 - nature.com
Sck, a member of the Shc family of cell signaling proteins, has only been studied in neuronal
cells, though previous studies have demonstrated its expression in tissues other than brain …
cells, though previous studies have demonstrated its expression in tissues other than brain …
Different signal transduction properties of KDR and Flt1, two receptors for vascular endothelial growth factor.
J Waltenberger, L Claesson-Welsh, A Siegbahn… - Journal of Biological …, 1994 - Elsevier
Vascular endothelial growth factor (VEGF) is a homodimeric peptide growth factor which
binds to two structurally related tyrosine kinase receptors denoted Flt1 and KDR. In order to …
binds to two structurally related tyrosine kinase receptors denoted Flt1 and KDR. In order to …
The Shb adaptor protein binds to tyrosine 766 in the FGFR-1 and regulates the Ras/MEK/MAPK pathway via FRS2 phosphorylation in endothelial cells
MJ Cross, L Lu, P Magnusson, D Nyqvist… - Molecular biology of …, 2002 - Am Soc Cell Biol
Stimulation of fibroblast growth factor receptor-1 (FGFR-1) is known to result in
phosphorylation of tyrosine 766 and the recruitment and subsequent activation of …
phosphorylation of tyrosine 766 and the recruitment and subsequent activation of …
Fibroblast growth factor receptor substrate 2 participates in vascular endothelial growth factor‐induced signaling
KV Stoletov, KE Ratcliffe, BI Terman - The FASEB Journal, 2002 - Wiley Online Library
Vascular endothelial growth factor (VEGF) activates endothelial cells, in part, by interacting
with the kinase insert domain‐containing receptor (KDR) receptor tyrosine kinase. Although …
with the kinase insert domain‐containing receptor (KDR) receptor tyrosine kinase. Although …
相关搜索
- growth factor receptor kdr
- growth factor adaptor protein
- vegf receptor shc adaptor
- adaptor protein receptor kdr
- growth factor endothelial cells
- transfected cells receptor kdr
- growth factor src homology
- tyrosine residues shc adaptor
- transfected cells adaptor protein
- tyrosine residues vegf receptor
- fgfr 1 endothelial cells
- cell proliferation receptor 1
- endothelial growth receptor kdr
- endothelial growth adaptor protein
- endothelial growth transfected cells
- growth factor transfected cells