Age-and function-related regional changes in cortical folding of the default mode network in older adults

C Jockwitz, S Caspers, S Lux, K Jütten… - Brain Structure and …, 2017 - Springer
Healthy aging is accompanied by changes in the functional architecture of the default mode
network (DMN), eg a posterior to anterior shift (PASA) of activations. The putative structural …

Age-related alterations in default mode network: impact on working memory performance

F Sambataro, VP Murty, JH Callicott, HY Tan, S Das… - Neurobiology of …, 2010 - Elsevier
The default mode network (DMN) is a set of functionally connected brain regions which
shows deactivation (task-induced deactivation, TID) during a cognitive task. Evidence shows …

Decreased default mode network connectivity correlates with age-associated structural and cognitive changes

D Vidal-Piñeiro, C Valls-Pedret… - Frontiers in aging …, 2014 - frontiersin.org
Ageing entails cognitive and motor decline as well as brain changes such as loss of gray
(GM) and white matter (WM) integrity, neurovascular and functional connectivity alterations …

Functional alteration patterns of default mode networks: comparisons of normal aging, amnestic mild cognitive impairment and Alzheimer's disease

J Cha, HJ Jo, HJ Kim, SW Seo, HS Kim… - European Journal of …, 2013 - Wiley Online Library
Most default mode network (DMN) studies in patients with amnestic mild cognitive
impairment (aMCI) and Alzheimer's disease (AD) are based on the comparison of only two …

Age and hippocampal volume predict distinct parts of default mode network activity

M De Marco, S Ourselin, A Venneri - Scientific reports, 2019 - nature.com
Group comparison studies have established that activity in the posterior part of the default-
mode network (DMN) is down-regulated by both normal ageing and Alzheimer's disease …

The default mode network in healthy aging and Alzheimer′ s disease

K Mevel, G Chételat, F Eustache… - International journal of …, 2011 - Wiley Online Library
In the past decade, a “default mode network”(DMN) has been highlighted in neuroimaging
studies as a set of brain regions showing increased activity in task‐free state compared to …

Dementia and the default mode

LL Beason-Held - Current Alzheimer Research, 2011 - ingentaconnect.com
Changes in regional activity levels and network connectivity occur across the lifespan within
the default mode network (DMN) of resting brain function. Changes with age are noted in …

Decreased fronto-parietal and increased default mode network activation is associated with subtle cognitive deficits in elderly controls

D Zanchi, ML Montandon, I Sinanaj, C Rodriguez… - Neurosignals, 2018 - karger.com
Background: Cognitive functions progressively deteriorate during aging and
neurodegenerative diseases. The present study aims at investigating differences in working …

[HTML][HTML] Longitudinal functional connectivity patterns of the default mode network in healthy older adults

B Malagurski, PF Deschwanden, L Jäncke, S Mérillat - NeuroImage, 2022 - Elsevier
Cross-sectional studies have consistently identified age-associated alterations in default
mode network (DMN) functional connectivity (FC). Yet, research on longitudinal trajectories …

Age‐related structural and functional variations in 5,967 individuals across the adult lifespan

N Luo, J Sui, A Abrol, D Lin, J Chen… - Human brain …, 2020 - Wiley Online Library
Exploring brain changes across the human lifespan is becoming an important topic in
neuroscience. Though there are multiple studies which investigated the relationship …