Platelet-mimetic synthetic hemostats are highly attractive in transfusion medicine. To this
end, past research reports have described particles that either amplify platelet aggregation …

Platelet transfusion is used for treating a variety of bleeding complications. Natural platelet-
based transfusion products have very short storage life (3–7 days) and high risks of …

There is substantial clinical interest in synthetic platelet analogs for potential application in
transfusion medicine. To this end, our research is focused on self-assembled peptide–lipid …

There is significant clinical interest in synthetic platelet substitutes that can mimic platelet's
hemostastic functionalities while allowing scale-up, minimal biological contamination, and …

Platelet adhesion, activation and fibrinogen-mediated aggregation are primary events in
vascular thrombosis and occlusion. An injectable delivery system that can carry …

Activated platelets play multiple roles in vascular diseases. Hence, a delivery vehicle that
can specifically target activated platelets and stay retained under a hemodynamic …

Treatment of bleeding disorders using transfusion of donor-derived platelets faces logistical
challenges due to their limited availability, high risk of contamination, and short (5 to 7 days) …

Targeted delivery of therapeutic and imaging agents in the vascular compartment represents
a significant hurdle in using nanomedicine for treating hemorrhage, thrombosis, and …

While there are currently many well-established topical hemostatic agents for field
administration, there are still limited tools to staunch bleeding at less accessible injury sites …

Platelets closely interface with the immune system to fight pathogens, target wound sites,
and regulate tissue repair. Natural platelet levels within the body can be depleted for a …