Effect of inhibition of prostaglandin synthesis on cervical softening and uterine activity during ovine parturition resulting from progesterone withdrawal induced by …

WL Ledger, MA Webster… - Journal of …, 1985 - joe.bioscientifica.com
The effects of an inhibitor of 3β-hydroxysteroid dehydrogenase (epostane) on uterine activity
and cervical softening have been studied in eight sheep during late pregnancy. Treatment …

Effects on maternal and fetal steroid concentrations of induction of parturition in the sheep by inhibition of 3β-hydroxysteroid dehydrogenase

M Silver - Reproduction, 1988 - rep.bioscientifica.com
Changes in circulating steroid hormones, the incidence of myometrial contractions, and the
onset of labour were all monitored after administration of the 3β-hydroxysteroid …

Inhibition of progesterone secretion by a 3β-hydroxysteroid dehydrogenase inhibitor in pregnant goats

MJ Taylor - Journal of endocrinology, 1987 - joe.bioscientifica.com
Epostane, an inhibitor of 3β-hydroxysteroid dehydrogenase, was administered to goats in
late pregnancy in the presence or absence of concurrent treatment with prostaglandin …

Use of meclofenamic acid to investigate the role of prostaglandin biosynthesis during induced parturition in sheep

MD Mitchell, APF Flint - Journal of Endocrinology, 1978 - joe.bioscientifica.com
The maternal administration of meclofenamic acid (a prostaglandin synthetase inhibitor) to
pregnant sheep prevented the dexamethasone-induced delivery of live lambs and delayed …

Effect of progesterone withdrawal in sheep during late pregnancy

MJ Taylor, R Webb, MD Mitchell… - Journal of …, 1982 - joe.bioscientifica.com
The concentration of progesterone in the peripheral plasma of seven sheep during late
pregnancy was reduced by injection of an inhibitor of 3β-hydroxysteroid dehydrogenase …

Failure of exogenous progestogens to block dexamethasone-induced prostaglandin F release from the uterus of the late-pregnant cow

RJ Fairclough, CC Kaltenbach, AJ Peterson… - Biology of …, 1984 - academic.oup.com
The effect of exogenous progesterone or megestrol acetate (MGA) on cervical extensibility
and on the concentrations of prostaglandin (PG) F in utero-ovarian plasma and …

Inhibition of 3β‐hydroxysteroid dehydrogenase in the sow near term: effects on fetal and maternal steroids and on delivery

M Silver, AL Fowden - Quarterly Journal of Experimental …, 1988 - Wiley Online Library
The effect of Epostane, a 3β‐hydroxysteroid dehydrogenase inhibitor, on maternal and fetal
plasma progesterone and other steroids has been investigated in chronically catheterized …

Effect of an inhibitor of 3β-hydroxysteroid dehydrogenase on progesterone concentrations and embryo survival in sheep

CJ Ashworth, I Wilmut, AJ Springbett… - Journal of …, 1987 - joe.bioscientifica.com
The effect of an inhibitor of 3β-hydroxysteroid dehydrogenase on peripheral progesterone
concentration during the luteal phase of the oestrous cycle and on embryo survival was …

Effects of inhibiting 3 beta-hydroxysteroid dehydrogenase on plasma progesterone and other steroids in the pregnant mare near term.

AL Fowden, M Silver - Journal of Reproduction and fertility …, 1987 - europepmc.org
Epostane, a competitive inhibitor of 3 beta-HSD was administered intravenously to a
pregnant mare between 292 and 330 days of gestation at doses of 1-3 mg/kg/min. Plasma …

[引用][C] Progesterone withdrawal: effects on prostaglandins and parturition

MD Mitchell, APF Flint - Prostaglandins, 1977 - Elsevier
Although the" Progesterone Block I1 hypothesis (1) has aroused great interest since its
proposal by Csapo in 1956, whether progesterone withdrawal either occurs or is necessary …