Radiation-induced damage to the retina triggers leukostasis, retinal endothelial cell (REC)
death, and subsequent hypoxia. Resultant ischemia leads to visual loss and compensatory …

Retinal microaneurysms, an early disease manifestation of diabetic retinopathy, are
associated with retinal endothelial cell (REC) death and macular edema. We previously …

Purpose.: To determine whether a novel NF-κB inhibitor, KZ-41, can inhibit melphalan's
actions on retinal endothelial cell (REC) inflammation and apoptosis, without eliminating the …

Background Inflammation and the excess production of reactive oxygen species (ROS)
contribute significantly to the pathogenesis of ischemic retinopathies such as diabetic …

Inflammation is a pathological hallmark of ischemia reperfusion (I/R) injury. The present
study was conducted to explore the ability of a new anti-inflammatory compound, X22, to …

Embolism, hyperglycemia, high intraocular pressure-induced increased reactive oxygen
species (ROS) production, and microglial activation result in endothelial/retinal ganglion cell …

Retinal ischemia–reperfusion (IR) injury is a basic pathological procedure in clinic and
associated with various ischemic retinal diseases, including glaucoma, diabetic retinopathy …

Abstract The Omi/HtrA2 inhibitor 5-[5-(2-nitrophenyl) furfuryliodine]-1, 3-diphenyl-2-
thiobarbituric acid (Ucf-101) has shown neuroprotective effects in the central nervous …

Purpose Inflammation and oxidative stress contribute to age-related macular degeneration
(AMD) and other retinal diseases. We tested a cell-penetrating peptide from the kinase …

Natural products are favored in the study of skin photodamage protection recently.
Isoquercetin, namely 3‐O‐glucoside of quercetin, can be isolated from various plant …