The release of nucleotides in extracellular fluids can result from cell necrosis, exocytosis of
secretory granules (such as platelet‐dense granules), vesicular trafficking, or efflux through …

Abstract P2Y receptors are G protein‐coupled receptors (GPCRs) that are activated by
adenine and uridine nucleotides and nucleotide sugars. There are eight subtypes of P2Y …

There have been many advances in our knowledge about different aspects of P2Y receptor
signaling since the last review published by our International Union of Pharmacology …

Nucleotides are ubiquitous intercellular messengers whose actions are mediated by specific
receptors. Since the first clonings in 1993, it is known that nucleotide receptors belong to two …

Membrane-bound P2-receptors mediate the actions of extracellular nucleotides in cell-to-
cell signalling. P2X-receptors are ligand-gated ion channels, whereas P2Y-receptors belong …

The P2 family of membrane-bound receptors is activated by naturally occurring nucleotides.
When activated, these widely distributed receptors elicit cellular signaling which mediate …

The action of extracellular nucleotides, specifically the ability of adenine nucleotides to
induce coronary vasodilation and bradycardia, was first described more than 70 years ago …

Membrane-bound P2-receptors mediate the actions of extracellular nucleotides in cell-to-
cell signalling. P2X-receptors are ligand-gated ion channels, whereas P2Y-receptors belong …

P2Y receptors are classified as P2 purinergic receptors that belong to the superfamily of G-
protein coupled receptors. They are distinguishable from P1 (adenosine) receptors in that …

Abstract P2Y receptors are G-protein-coupled receptors (GPCRs) for extracellular
nucleotides. There are eight mammalian P2Y receptor subtypes (P2Y 1, P2Y 2, P2Y 4, P2Y …