Biological formation and consumption of molecular hydrogen (H2) are catalyzed by
hydrogenases, of which three phylogenetically unrelated types are known:[NiFe] …

Ever since the discovery of hydrogenases over 90 years ago (Stephenson and Stickland,
1931), their structure and mechanism of action have been intensively investigated. Of the …

The enzyme hydrogenase, from the photosyn-thetic bacterium Chromatium, was purified to
homogeneity after solubilization of the particulate enzyme with deoxy-cholate. The …

Many microorganisms can use molecular hydrogen as a source of electrons or generate it
by reducing protons. These reactions are catalysed by metalloenzymes of two types: NiFe …

Conspectus Hydrogenases are metalloenzymes that catalyze proton reduction and H2
oxidation with outstanding efficiency. They are model systems for bioinorganic chemistry …

Hydrogenases are redox enzymes that catalyze the conversion of protons and molecular
hydrogen (H2). Based on the composition of the active site cofactor, the monometallic [Fe] …

Hydrogenases are biological catalysts for hydrogen evolution and activation. While many
model complexes of hydrogenases can catalyze the hydrogen evolution reaction, few of …

Dihydrogen has the potential to act as a “clean''alternative to fossil fuels. 1 The oxidation of
dihydrogen, either electrochemically or via combustion, leads only to the production of …

Hydrogenases catalyze the reversible conversion of molecular hydrogen to protons and
electrons via a heterolytic splitting mechanism. The active sites of [NiFe] hydrogenases …

Crystallographic data on the [NiFe] hydrogenase from Desulfovibrio gigas are presented that
provide new information on the structure and mode of action of its dihydrogen activating …