[HTML][HTML] Chemical trends in sample preparation for nucleic acid amplification testing (NAAT): a Review

SM Lee, HK Balakrishnan, EH Doeven, D Yuan… - Biosensors, 2023 - mdpi.com
Nucleic acid amplification testing facilitates the detection of disease through specific
genomic sequences and is attractive for point-of-need testing (PONT); in particular, the early …

Sample preparation: a challenge in the development of point-of-care nucleic acid-based assays for resource-limited settings

MA Dineva, L Mahilum-Tapay, H Lee - Analyst, 2007 - pubs.rsc.org
Currently available nucleic acid testing (NAT)-based assays are complex and time-
consuming, and they require expensive instrumentation and dedicated laboratory spaces for …

[HTML][HTML] Advances in directly amplifying nucleic acids from complex samples

FM Walker, K Hsieh - Biosensors, 2019 - mdpi.com
Advances in nucleic acid amplification technologies have revolutionized diagnostics for
systemic, inherited, and infectious diseases. Current assays and platforms, however, often …

Technical considerations for the performance of Nucleic acid Amplification Technology (NAT): The NAT Task Force Group

M Chudy, I Hewlett, J Saldanha, C Bianco, AJ Conrad… - Biologicals, 2003 - Elsevier
The complexity of Nucleic acid Amplification Technology (NAT1), comprising sample
preparation, amplification and detection methods, requires specific design considerations for …

[HTML][HTML] Enzyme-assisted nucleic acid amplification in molecular diagnosis: a review

M Wang, H Liu, J Ren, Y Huang, Y Deng, Y Liu, Z Chen… - Biosensors, 2023 - mdpi.com
Infectious diseases and tumors have become the biggest medical challenges in the 21st
century. They are driven by multiple factors such as population growth, aging, climate …

[HTML][HTML] Simple approaches to minimally-instrumented, microfluidic-based point-of-care nucleic acid amplification tests

MG Mauk, J Song, C Liu, HH Bau - Biosensors, 2018 - mdpi.com
Designs and applications of microfluidics-based devices for molecular diagnostics (Nucleic
Acid Amplification Tests, NAATs) in infectious disease testing are reviewed, with emphasis …

Nucleic Acid Amplification‐Based Technologies (NAAT)—Toward Accessible, Autonomous, and Mobile Diagnostics

V Narasimhan, H Kim, SH Lee, H Kang… - Advanced Materials …, 2023 - Wiley Online Library
The ongoing pandemic and increasing frequency of infectious disease outbreaks due to
climate change, urbanization, and global human migration have put great focus on nucleic …

[HTML][HTML] Democratizing nucleic acid-based molecular diagnostic tests for infectious diseases at resource-limited settings–from point of care to extreme point of care

S Chakraborty - Sensors & Diagnostics, 2024 - pubs.rsc.org
The recurring instances of infectious disease outbreaks, coupled with complications such as
comorbidity challenges and antibiotic resistance, consistently underscore the limitations …

Noninstrumented nucleic acid amplification assay

BH Weigl, G Domingo, J Gerlach… - Microfluidics …, 2008 - spiedigitallibrary.org
We have developed components of a diagnostic disposable platform that has the dual
purpose of providing molecular diagnostics at the point of care (POC) as well as stabilizing …

Low-cost colorimetric reader and label-free strategy for user-friendly detection of nucleic acid amplification products

W Tang, M Zhang, T Yue, X Wang, Z Li - Sensors and Actuators B …, 2021 - Elsevier
Analyses of nucleic acid amplification products are generally performed by the complicated
gel electrophoresis or costly florescence method. In this work, colorimetric detection of …