The concept of biomarkers of aging and age-related disease dates to the early 1980s as
scientists engaged in aging research worked to clearly define aging and separate processes …

The escalating interest in research on interventions that may affect aging processes has
necessarily focussed attention on the outcome measures. The desirable characteristics of …

Leading biologists and clinicians interested in aging convened to discuss biomarkers of
aging. The goals were to come to a consensus, construct an agenda for future research, and …

This article presents a conceptual discussion of some aspects involved in biomarkers in
aging. A biomarker of aging is a biological parameter of an organism that either alone or in …

The identification of specific biomarkers of aging would be an important milestone in
gerontologic research. In this communication, the goals of identifying biomarkers of aging …

A series of questions is presented regarding a logical strategy for developing biomarkers of
aging. The questions pertain to the conceptualization process in determining how to define …

Much progress has been made in the past decades in unraveling the mechanisms that are
responsible for aging. The discovery that particular gene mutations in experimental species …

If effective anti-aging interventions are to be identified for human application, then the
development of reliable and valid biomarkers of aging are essential for this progress …

No intervention will slow, stop, or reverse the aging process in humans. Whether anti-aging
medicine is, or is not, a legitimate science is completely dependent upon the definition of key …

Claims of accelerated or premature aging are frequently made. However, the lack of
standard criteria for measuring speed of aging makes such claims highly questionable …