Pharmacological evaluation of mangiferin herbosomes for antioxidant and hepatoprotection potential against ethanol induced hepatic damage

PK Jain, M Kharya, A Gajbhiye - Drug Development and Industrial …, 2013 - Taylor & Francis
Context: Fatty liver is the first stage of alcoholic damage which is reversible with abstinence
from alcohol. Mangiferin (MF) showed potent scavenging activity on diphenyl-1 …

Mangiferin ameliorates intracerebroventricular-quinolinic acid-induced cognitive deficits, oxidative stress, and neuroinflammation in Wistar rats

MK Arora, A Kisku, A Jangra - Indian Journal of Pharmacology, 2020 - journals.lww.com
MATERIALS AND METHODS: QA (300 nm/4 μl saline) was administered
intracerebroventricular in the striatum (unilaterally) once. Thereafter, MGF 20 and 40 mg/kg …

The suppressive effect of mangiferin with exercise on blood lipids in type 2 diabetes

T MIURA, N IWAMOTO, M KATO, H ICHIKI… - Biological and …, 2001 - jstage.jst.go.jp
MATERIALS AND METHODS Materials MF was isolated by a conventional method as
previously reported. 1) The structure of MF was confirmed by the spectroscopic method. 4) …

Effects of Mangiferin on Glucose and Lipid Metabolism of Insulin-resistant HepG2 Cells

Z LI, H JIN, J FANG, Y LIU, A LIN - China Pharmacy, 2021 - pesquisa.bvsalud.org
OBJECTIVE: To analyze the effects of mangiferin (MGF) on glucose and lipid metabolism in
insulin resistance (IR) HepG2 cells, and to explore the potential mechanism. METHODS …

[HTML][HTML] In-depth analysis of the chemical composition, pharmacological effects, pharmacokinetics, and patent history of mangiferin

M Kaurav, J Kanoujia, M Gupta, P Goyal, S Pant… - Phytomedicine Plus, 2023 - Elsevier
Abstract Introduction Mangiferin (2-D-glucopyranosyl-1, 3, 6, 7-tetrahydroxy-9H-xanthen-9-
one) is extracted from different part of plants such seed, peel, and kernels of mango …

Metabolomic analysis for the protective effects of mangiferin on sepsis‐induced lung injury in mice

Y Wang, Y Liu, Q Cao, X Shi, H Lu… - Biomedical …, 2018 - Wiley Online Library
This study aimed to investigate the efficacy of mangiferin, including its known antioxidant
and anti‐inflammatory effects on sepsis‐induced lung injury induced by a classical cecal …

Mangiferin: A multipotent natural product preventing neurodegeneration in Alzheimer's and Parkinson's disease models

ST Feng, ZZ Wang, YH Yuan, HM Sun, NH Chen… - Pharmacological …, 2019 - Elsevier
Alzheimer's disease (AD) and Parkinson's disease (PD) are recognized as the universal
neurodegenerative diseases, with the involvement of misfolded proteins pathology, leading …

Dual mode action of mangiferin in mouse liver under high fat diet

J Lim, Z Liu, P Apontes, D Feng, JE Pessin, AA Sauve… - PloS one, 2014 - journals.plos.org
Chronic over-nutrition is a major contributor to the spread of obesity and its related metabolic
disorders. Development of therapeutics has been slow compared to the speedy increase in …

Effect of mangiferin with exercise in early stage symptom of type 2 diabetic mice

N IWAMOTO, T MIURA, M KATO, T TAKEMOTO… - Biomedical …, 2000 - jstage.jst.go.jp
The antidiabetic action of mangiferin (MF) with exercise was investigated in KK-Ay mice, an
animal model of type 2 diabetes. MF (30 mg/kg) significantly decreased the blood glucose …

Mangiferin exerts neuroprotective effects against focal cerebral ischemia in mice by regulating NF-κB signaling pathway

T Hao, C Chen, S Yang, Y Zhang, F Liang - Metabolic Brain Disease, 2023 - Springer
Purpose: Mangiferin is a natural free radical scavenging antioxidant that induces excitation
of the central nervous system. However, the mechanism of neuroprotective effect of …