Isolated mangiferin and naringenin exert antidiabetic effect via PPARγ/GLUT4 dual agonistic action with strong metabolic regulation

AK Singh, V Raj, AK Keshari, A Rai, P Kumar… - Chemico-Biological …, 2018 - Elsevier
In this study, we isolated two compounds from the leaves of Salacia oblonga (SA1,
mangiferin and SA2, naringenin), and their structures were confirmed by infrared …

Neuroprotective potency of mangiferin against 3-nitropropionic acid induced Huntington's disease-like symptoms in rats: possible antioxidant and anti-inflammatory …

PT Lum, M Sekar, LJ Seow, MF Shaikh… - Frontiers in …, 2023 - frontiersin.org
Huntington's disease (HD), a neurodegenerative disease, normally starts in the prime of
adult life, followed by a gradual occurrence of psychiatric disturbances, cognitive and motor …

Predicting the targets of mangiferin in the treatment of diabetes mellitus on network pharmacology and analysis of its metabolites in vivo

Y Wei, X Li, X Su, T Xu - Pharmacognosy Magazine, 2022 - phcog.com
Background: The number of diabetic patients worldwide continues to increase. Diabetes
mellitus (DM) has become one of the three chronic diseases threatening human health …

Evaluation of Antiobesity Effect of Mangiferin in Adipogenesis‐Induced Human Mesenchymal Stem Cells by Assessing Adipogenic Genes

P Subash‐Babu, AA Alshatwi - Journal of Food Biochemistry, 2015 - Wiley Online Library
We aimed to examine the anti‐adipogenic effects of mangiferin (xanthone glucoside) and its
related mechanism. Human mesenchymal stem cells (hMSCs) were cultured in D ulbecco's …

Mangiferin and organ fibrosis: a mini review

L Zhang, C Huang, S Fan - Biofactors, 2021 - Wiley Online Library
Fibrosis is the end stage of many chronic diseases, which results in organ function failure
and high mortality. Mangiferin is a major constituent in mango and other 16 plants, and has …

[PDF][PDF] Protective effect of mangiferin on doxorubicin-induced liver damage in animal model

F Husna, W Arozal, H Yusuf… - Journal of Research in …, 2022 - academia.edu
Mangiferin is a bioactive compound which has antioxidant effect, but its effect on liver
protection during chemotherapy with doxorubicin is understudied. The objective of this study …

[引用][C] Investigation of acute, sub-chronic toxicity, effects of mangiferin and mangiferin solid dispersion (HPTR) on Triton WR1339-induced hyperlipidemia on Swiss …

DTM Huynh, LM Le, LT Nguyen, THN Nguyen… - …, 2024 - pharmacia.pensoft.net
Mangiferin is a xanthonoid found in Mango leaves in abundance with many effects as a
hypoglycemic, antioxidant, and anti-inflammatory agent, plant metabolite, and so on …

Mangiferin suppressed advanced glycation end products (AGEs) through NF-κB deactivation and displayed anti-inflammatory effects in streptozotocin and high fat diet …

J Hou, D Zheng, G Fung, H Deng… - Canadian journal of …, 2016 - cdnsciencepub.com
Given the importance of the aggregation of advanced glycation end products (AGEs) and
cardiac inflammation in the onset and progression of diabetic cardiomyopathy (DCM), our …

Purification Process of Mangiferin from Mangifera indica L. Leaves and Evaluation of Its Bioactivities

NTT Loan, DT Long, PND Yen, TTM Hanh, TN Pham… - Processes, 2021 - mdpi.com
Mangiferin (C19H18O11) is a C-glucoside xanthone that is mainly found in the leaves of
mango (Mangifera indica L). The compound has been recognized for several …

Mangiferin upregulates glyoxalase 1 through activation of Nrf2/ARE signaling in central neurons cultured with high glucose

YW Liu, YQ Cheng, XL Liu, YC Hao, Y Li, X Zhu… - Molecular …, 2017 - Springer
Mangiferin, a natural C-glucoside xanthone, has anti-inflammatory, anti-oxidative,
neuroprotective actions. Our previous study showed that mangiferin could attenuate …