From Compassionate Use to Phase 3 Trial: The Impact of Germany's PSMA-617 Literature (perspective on “German Multicenter Study Investigating 177Lu-PSMA-617 …

TA Hope - Journal of Nuclear Medicine, 2020 - Soc Nuclear Med
Results: A total of 248 therapy cycles were performed in 145 patients. Data for biochemical
response in 99 patients as well as data for physician-reported and laboratory-based toxicity …

German multicenter study investigating 177Lu-PSMA-617 radioligand therapy in advanced prostate cancer patients

K Rahbar, H Ahmadzadehfar… - Journal of Nuclear …, 2017 - Soc Nuclear Med
177Lu-labeled PSMA-617 is a promising new therapeutic agent for radioligand therapy
(RLT) of patients with metastatic castration-resistant prostate cancer (mCRPC). Initiated by …

First experience with 177Lu-PSMA-617 therapy for advanced prostate cancer in the Netherlands

L van Kalmthout, A Braat, M Lam… - Clinical nuclear …, 2019 - journals.lww.com
Purpose The present study summarizes the first experience with 177 Lu-PSMA-617 (177 Lu-
PSMA) treatment in metastatic castration-resistant prostate cancer (PCa) in our institution …

Treatment outcome and identification of factors influencing overall survival after Lu-177-PSMA-617 radioligand therapy in metastatic prostate cancer

CA Schneider, P Täger, J Hammes… - Nuklearmedizin …, 2022 - thieme-connect.com
Objective To examine the clinical benefit of Lu-177-PSMA-617 radioligand therapy for
patients with metastatic castration-resistant prostate cancer (mCRPC). Patients and Methods …

[HTML][HTML] Clinical outcome of standardized 177Lu-PSMA-617 therapy in metastatic prostate cancer patients receiving 7400 MBq every 4 weeks

S Rasul, M Hacker, E Kretschmer-Chott… - European journal of …, 2020 - Springer
Abstract Purpose [177 Lu] Lu-PSMA-617 radio-ligand therapy (PSMA-RLT) is emerging in
patients with an advanced metastatic castration-resistant prostate cancer (mCRPC). Here …

[HTML][HTML] 177 Lu-PSMA-617 radioligand therapy of metastatic castration-resistant prostate cancer: Initial 254-patient results from a prospective registry (REALITY Study)

F Khreish, Z Ghazal, RJ Marlowe, F Rosar… - European Journal of …, 2022 - Springer
Purpose Preliminary data from retrospective analyses and recent data from large
randomized controlled trials suggest safety and efficacy of radioligand therapy (RLT) …

177Lu-PSMA-617 therapy, dosimetry and follow-up in patients with metastatic castration-resistant prostate cancer

WP Fendler, C Kratochwil… - Nuklearmedizin …, 2016 - europepmc.org
Radioligand therapy (RLT) using 177Lu labelled inhibitors of the prostate-specific
membrane antigen (177Lu-PSMA) is performed in patients with metastatic castration …

Safety and efficacy of 177lu-PSMA-617 radioligand therapy in patients with mCRPC: A multicenter study.

K Rahbar, H Ahmadzadehfar, C Kratochwil, RP Baum… - 2017 - ascopubs.org
155 Background: Prostate specific membrane antigen (PSMA) is a promising target for
imaging and therapy of prostate cancer. Small cohorts trials have shown promising results …

Efficacy and safety of 177Lu-PSMA-617 radioligand therapy in metastatic castration-resistant prostate cancer patients

MP Yadav, S Ballal, C Bal, RK Sahoo… - Clinical nuclear …, 2020 - journals.lww.com
Purpose The aim of this study was to evaluate the efficacy and safety of 177 Lu-PSMA-617
radioligand therapy in metastatic castration-resistant prostate cancer (mCRPC). Methods In …

[177Lu]-PSMA-617 radionuclide treatment in patients with metastatic castration-resistant prostate cancer (LuPSMA trial): a single-centre, single-arm, phase 2 study

MS Hofman, J Violet, RJ Hicks, J Ferdinandus… - The Lancet …, 2018 - thelancet.com
Background Progressive metastatic castration-resistant prostate cancer is a highly lethal
disorder and new effective therapeutic agents that improve patient outcomes are urgently …