Abstract Johnston, CJ, Williams, JP, Okunieff, P. and Finkelstein, JN Radiation-Induced
Pulmonary Fibrosis: Examination of Chemokine and Chemokine Receptor Families. Radiat …

Lung exposure to radiation induces an injury response that includes the release of cytokines
and chemotactic mediators; these signals recruit immune cells to execute inflammatory and …

Patients receiving thoracic radiation often develop pulmonary injury and fibrosis. Currently,
there are no effective measures to prevent or treat these conditions. We tested whether …

Fibrosis, characterized by the accumulation of collagen, is a consequence of a chronic
inflammatory response. The purpose of this study was to determine if the mRNA expression …

Background/Aim: We compared pulmonary irradiation-induced whole-lung, gene transcripts
over 200 days after 20 Gy thoracic irradiation in female fibrosis-prone C57BL/6NHsd mice …

Ionizing radiation leads to a progressive injury in which a monocyte/macrophage-rich
pneumonitis is followed by a chronic progressive fibrosis. In the present study, the role of …

Background Recent research has supported that a variety of cytokines play important roles
during radiation-induced lung toxicity. The present study is designed to investigate the …

Pulmonary fibrosis is caused by various known and unknown aetiologies, but the key
pathogenic mechanisms are still ill-defined. Chemokines are a large family of chemotactic …

Purpose: Radiation-induced pulmonary reactions have classically been viewed as distinct
phases-acute pneumonitis and, later, fibrosis-occurring at different times after irradiation and …

Background A devastating late injury caused by radiation is pulmonary fibrosis. This risk
may limit the volume of irradiation and compromise potentially curative therapy. Therefore …