Data-driven identification of intensity normalization region based on longitudinal coherency of 18F-FDG metabolism in the healthy brain

H Zhang, P Wu, SI Ziegler, Y Guan, Y Wang, J Ge… - Neuroimage, 2017 - Elsevier
Abstract Objectives In brain 18 F-FDG PET data intensity normalization is usually applied to
control for unwanted factors confounding brain metabolism. However, it can be difficult to …

The pons as reference region for intensity normalization in semi-quantitative analysis of brain 18FDG PET: application to metabolic changes related to ageing in …

A Verger, M Doyen, JY Campion, E Guedj - EJNMMI research, 2021 - Springer
Background The objective of the study is to define the most appropriate region for intensity
normalization in brain 18 FDG PET semi-quantitative analysis. The best option could be …

Voxel-based analysis of [18F]-FDG brain PET in rats using data-driven normalization

S Proesmans, R Raedt, C Germonpré… - Frontiers in …, 2021 - frontiersin.org
Introduction:[18F]-FDG PET is a widely used imaging modality that visualizes cellular
glucose uptake and provides functional information on the metabolic state of different tissues …

[HTML][HTML] Intensity normalization methods in brain FDG-PET quantification

FJ López-González, J Silva-Rodríguez… - Neuroimage, 2020 - Elsevier
Background The lack of standardization of intensity normalization methods and its unknown
effect on the quantification output is recognized as a major drawback for the harmonization …

Selection of the optimal intensity normalization region for FDG-PET studies of normal aging and Alzheimer's disease

S Nugent, E Croteau, O Potvin, CA Castellano… - Scientific reports, 2020 - nature.com
The primary method for measuring brain metabolism in humans is positron emission
tomography (PET) imaging using the tracer 18F-fluorodeoxyglucose (FDG). Standardized …

Longitudinal progression of cognitive decline correlates with changes in the spatial pattern of brain 18F-FDG PET

S Shokouhi, D Claassen, H Kang, Z Ding… - Journal of Nuclear …, 2013 - Soc Nuclear Med
Evaluating the symptomatic progression of mild cognitive impairment (MCI) caused by
Alzheimer disease (AD) is practically accomplished by tracking performance on cognitive …

Validation of FDG-PET datasets of normal controls for the extraction of SPM-based brain metabolism maps

SP Caminiti, A Sala, L Presotto, A Chincarini… - European journal of …, 2021 - Springer
Purpose An appropriate healthy control dataset is mandatory to achieve good performance
in voxel-wise analyses. We aimed at evaluating [18F] FDG PET brain datasets of healthy …

[HTML][HTML] Volume of interest-based [18F] fluorodeoxyglucose PET discriminates MCI converting to Alzheimer's disease from healthy controls. A European Alzheimer's …

M Pagani, F De Carli, S Morbelli, J Öberg… - NeuroImage: Clinical, 2015 - Elsevier
An emerging issue in neuroimaging is to assess the diagnostic reliability of PET and its
application in clinical practice. We aimed at assessing the accuracy of brain FDG-PET in …

A novel individual metabolic brain network for 18F-FDG PET imaging

SY Huang, JL Hsu, KJ Lin, IT Hsiao - Frontiers in neuroscience, 2020 - frontiersin.org
Introduction Metabolic brain network analysis based on graph theory using FDG PET
imaging is potentially useful for investigating brain activity alternation due to metabolism …

[HTML][HTML] Greater accuracy of radiomics compared to deep learning to discriminate normal subjects from patients with dementia: a whole brain 18FDG PET analysis

A Bestetti, L Calabrese, V Parini… - Nuclear Medicine …, 2024 - journals.lww.com
Objective FDG PET imaging plays a crucial role in the evaluation of demented patients by
assessing regional cerebral glucose metabolism. In recent years, both radiomics and deep …