Secretomes from mesenchymal stem cells against acute kidney injury: possible heterogeneity
K Tsuji, S Kitamura, J Wada - Stem cells international, 2018 - Wiley Online Library
A kidney has the ability to regenerate itself after a variety of renal injuries. Mesenchymal
stem cells (MSCs) have been shown to ameliorate tissue damages during renal injuries and …
stem cells (MSCs) have been shown to ameliorate tissue damages during renal injuries and …
[HTML][HTML] Immunomodulatory and regenerative effects of mesenchymal stem cell-derived extracellular vesicles in renal diseases
K Tsuji, S Kitamura, J Wada - International journal of molecular sciences, 2020 - mdpi.com
Mesenchymal stem cells (MSCs) have immunomodulatory and regenerative effects in many
organs, including the kidney. Emerging evidence has shown that the trophic effects from …
organs, including the kidney. Emerging evidence has shown that the trophic effects from …
[HTML][HTML] Mesenchymal stem cell-derived extracellular vesicles for kidney repair: current status and looming challenges
A Aghajani Nargesi, LO Lerman, A Eirin - Stem cell research & therapy, 2017 - Springer
Novel therapies are urgently needed to address the rising incidence and prevalence of
acute kidney injury (AKI) and chronic kidney disease (CKD). Mesenchymal stem/stromal …
acute kidney injury (AKI) and chronic kidney disease (CKD). Mesenchymal stem/stromal …
[HTML][HTML] Molecular mechanisms of mesenchymal stem cell-based therapy in acute kidney injury
Acute kidney injury (AKI) causes a lot of harm to human health but is treated by only
supportive therapy in most cases. Recent evidence shows that mesenchymal stem cells …
supportive therapy in most cases. Recent evidence shows that mesenchymal stem cells …
Mesenchymal stem cell-derived extracellular vesicles for renal repair
A Aghajani Nargesi, LO Lerman… - Current gene therapy, 2017 - ingentaconnect.com
Introduction: Transplantation of autologous mesenchymal stem cells (MSCs) has been
shown to attenuate renal injury and dysfunction in several animal models, and its efficacy is …
shown to attenuate renal injury and dysfunction in several animal models, and its efficacy is …
[HTML][HTML] Mesenchymal stem cell-derived extracellular vesicles to the rescue of renal injury
L Birtwistle, XM Chen, C Pollock - International Journal of Molecular …, 2021 - mdpi.com
Acute kidney injury (AKI) and chronic kidney disease (CKD) are rising in global prevalence
and cause significant morbidity for patients. Current treatments are limited to slowing instead …
and cause significant morbidity for patients. Current treatments are limited to slowing instead …
[HTML][HTML] Mesenchymal stromal cells secretome restores bioenergetic and redox homeostasis in human proximal tubule cells after ischemic injury
J Faria, S Calcat-i-Cervera, R Skovronova… - Stem cell research & …, 2023 - Springer
Background Ischemia/reperfusion injury is the leading cause of acute kidney injury (AKI).
The current standard of care focuses on supporting kidney function, stating the need for …
The current standard of care focuses on supporting kidney function, stating the need for …
Mesenchymal stem cells in kidney repair
Every year 13.3 million people suffer acute kidney injury (AKI), which is associated with a
high risk of death or development of long-term chronic kidney disease (CKD) in a substantial …
high risk of death or development of long-term chronic kidney disease (CKD) in a substantial …
[HTML][HTML] The effects of glomerular and tubular renal progenitors and derived extracellular vesicles on recovery from acute kidney injury
A Ranghino, S Bruno, B Bussolati, A Moggio… - Stem cell research & …, 2017 - Springer
Abstract Background Mesenchymal stromal cells (MSCs) and renal stem/progenitors
improve the recovery of acute kidney injury (AKI) mainly through the release of paracrine …
improve the recovery of acute kidney injury (AKI) mainly through the release of paracrine …
[HTML][HTML] Stem cell-derived extracellular vesicles and kidney regeneration
C Grange, R Skovronova, F Marabese, B Bussolati - Cells, 2019 - mdpi.com
Extracellular vesicles (EVs) are membranous vesicles containing active proteins, lipids, and
different types of genetic material such as miRNAs, mRNAs, and DNAs related to the …
different types of genetic material such as miRNAs, mRNAs, and DNAs related to the …
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