We have performed high-resolution fluid–structure interaction simulations of physiologic
pulsatile flow through a bi-leaflet mechanical heart valve (BMHV) in an anatomically realistic …

The goal of this study has been to develop a numerical model of the aortic valve, to validate
it with in-vivo data and to computationally evaluate the effect of two types of aortic valve …

The analysis of quantitative hemodynamics provides information for the diagnosis and
treatment planning in patients with aortic coarctation (CoA). Patient-specific computational …

A three-dimensional (3-D) pulsatile aortic flow in a human ascending aorta is studied to
investigate the effect of the aortic stiffness on the flow field and turbulent fluctuating velocities …

Objectives: We sought to clarify the role of isovolumic intervals during a cardiac cycle by in
vivo visualization of left ventricular (LV) intracavitary flow dynamics. Background …

Pathologies of the aortic valve such as aortic sclerosis are thought to impact coronary blood
flow. Recent clinical investigations have observed simultaneous structural and …

Abdominal aortic aneurysm (AAA) is characterized by disturbed blood flow patterns that are
hypothesized to contribute to disease progression. The transport topology in six patient …

In a chamber of the heart, large-scale vortices are shown to exist as the result of the dynamic
blood flow and unique morphological changes of the chamber wall. As the cardiovascular …

Introduction Phase contrast MRI allows for the examination of complex hemodynamics in the
heart and adjacent great vessels. Vortex flow patterns seem to play an important role in …

Valvular heart disease has recently become an increasing public health concern due to the
high prevalence of valve degeneration in aging populations. For patients with severely …