Experimental investigation of the influence of the aortic stiffness on hemodynamics in the ascending aorta

U Gülan, B Lüthi, M Holzner, A Liberzon… - IEEE journal of …, 2014 - ieeexplore.ieee.org
A three-dimensional (3-D) pulsatile aortic flow in a human ascending aorta is studied to
investigate the effect of the aortic stiffness on the flow field and turbulent fluctuating velocities …

Characterization of the transport topology in patient-specific abdominal aortic aneurysm models

A Arzani, SC Shadden - Physics of Fluids, 2012 - pubs.aip.org
Abdominal aortic aneurysm (AAA) is characterized by disturbed blood flow patterns that are
hypothesized to contribute to disease progression. The transport topology in six patient …

High-resolution fluid–structure interaction simulations of flow through a bi-leaflet mechanical heart valve in an anatomic aorta

I Borazjani, L Ge, F Sotiropoulos - Annals of biomedical engineering, 2010 - Springer
We have performed high-resolution fluid–structure interaction simulations of physiologic
pulsatile flow through a bi-leaflet mechanical heart valve (BMHV) in an anatomically realistic …

The effect of aortic wall and aortic leaflet stiffening on coronary hemodynamic: a fluid–structure interaction study

S Nobari, R Mongrain, R Leask, R Cartier - Medical & biological …, 2013 - Springer
Pathologies of the aortic valve such as aortic sclerosis are thought to impact coronary blood
flow. Recent clinical investigations have observed simultaneous structural and …

Hemodynamics in Patients with Aortic Coarctation: A Comparison of in vivo 4D-Flow MRI and FSI Simulation

PJ Nair, MR Pfaller, SA Dual, M Loecher… - … on Functional Imaging …, 2023 - Springer
The analysis of quantitative hemodynamics provides information for the diagnosis and
treatment planning in patients with aortic coarctation (CoA). Patient-specific computational …

Cardiac flow component analysis

KKL Wong, J Tu, RM Kelso, SG Worthley… - Medical engineering & …, 2010 - Elsevier
In a chamber of the heart, large-scale vortices are shown to exist as the result of the dynamic
blood flow and unique morphological changes of the chamber wall. As the cardiovascular …

Computational modelling and analysis of haemodynamics in a simple model of aortic stenosis

C Zhu, JH Seo, R Mittal - Journal of Fluid Mechanics, 2018 - cambridge.org
In a study motivated by considerations associated with heart murmurs and cardiac
auscultation, numerical simulations are used to analyse the haemodynamics in a simple …

Jet collisions and vortex reversal in the human left ventricle

G Di Labbio, L Kadem - Journal of biomechanics, 2018 - Elsevier
Unnatural dynamics of the notorious vortex in the left ventricle is often associated with
cardiac disease. Understanding how different cardiac diseases alter the flow physics in the …

Thinner biological tissues induce leaflet flutter in aortic heart valve replacements

EL Johnson, MCH Wu, F Xu… - Proceedings of the …, 2020 - National Acad Sciences
Valvular heart disease has recently become an increasing public health concern due to the
high prevalence of valve degeneration in aging populations. For patients with severely …

Direction and magnitude of blood flow shear stresses on the leaflets of aortic valves: is there a link with valve calcification?

L Ge, F Sotiropoulos - 2010 - asmedigitalcollection.asme.org
Aortic stenosis caused by valve calcification is a major cause of death around the world.
Hemodynamic factors have been suggested to be major players in the development of valve …